The blood–brain barrier (BBB) plays a vital role in protecting the central nervous system
(CNS) by preventing the entry of harmful pathogens from the bloodstream. However, this …

According to the DSM-5, neurodevelopmental disorders represent a group of
heterogeneous conditions, with onset during the developmental period, characterized by an …

Oxidative stress, characterized by increased production of reactive oxygen species (ROS)
and disturbed redox homeostasis, is one of the key mechanisms underlying synaptic loss …

ABSTRACT Introduction Status Epilepticus (SE) stands as a prominent neurological
emergency, showing a mortality rate of approximately 20%. Since February 2021, a …

Status epilepticus (SE) is a medical and neurologic emergency that may lead to permanent
brain damage, morbidity, or death. Animal models of SE are particularly important to study …

Introduction The last few decades have increased our understanding of autoimmune
encephalitis (AE). In both the pediatric and adult populations, it proves to be a disease of …

Objective To investigate the short-term benefits and adverse effects of ketamine in the
treatment of pediatric and adolescent super-refractory status epilepticus (SRSE), with a …

Our study investigated the causal relationship between immune cells, metabolites, and
epilepsy using two-sample Mendelian Randomization (MR) and mediation MR analysis of …

Refractory epilepsy, characterized by seizures that do not respond to standard antiseizure
medications, remains a significant clinical challenge. The central role of the immune system …

Of all patients with brain tumors, about 30–50% suffer from epileptic seizures. The
probability of develo** epilepsy is particularly high in low-grade, epilepsy-associated …