Type 1 diabetes mellitus (T1DM) is the most common chronic autoimmune disease in young
patients and is characterized by the loss of pancreatic β cells; as a result, the body becomes …

Basic and clinical research accomplished during the last few years on embryonic, fetal,
amniotic, umbilical cord blood, and adult stem cells has constituted a revolution in …

Mesenchymal stem cells (MSCs) have important tissue repair functions and show potent
immunosuppressive capacities in vitro. Although usually isolated from the bone marrow …

Of all the cell types that can be obtained from the differentiation of embryonic stem cells,
primordial germ cells are arguably the most fascinating, as they represent the in vitro …

Background Nestin is an intermediate filament first reported in neuroepithelial stem cells.
Nestin expression could be found in a variety of tissues throughout all systems of the body …

Mesenchymal stem cells (MSCs) have already made their mark in the young field of
regenerative medicine. Easily derived from many adult tissues, their therapeutic worth has …

Generation of surrogate β-cells is the need of the day to compensate the short supply of
islets for transplantation to diabetic patients requiring daily shots of insulin. Over the years …

Islet transplantation offers improved glucose homeostasis in diabetic patients, but
transplantation of islets is limited by the supply of donor pancreases. Undifferentiated …

The progressive decline and eventual loss of islet β-cell function underlies the
pathophysiological mechanism of the development of both type 1 and type 2 diabetes …

• Introduction• Biological characterization of mesenchymal stem cells‐Isolation and culture of
human MSCs‐Phenotypic properties of MSCs‐Multi‐potent differentiation of MSCs …