A review of caffeine's effects on cognitive, physical and occupational performance

TM McLellan, JA Caldwell, HR Lieberman - Neuroscience & Biobehavioral …, 2016 - Elsevier
Caffeine is consumed by over 80% of US adults. This review examines the effects caffeine
has on cognitive and physical function, since most real-world activities require complex …

International society of sports nutrition position stand: caffeine and exercise performance

NS Guest, TA VanDusseldorp, MT Nelson… - Journal of the …, 2021 - Taylor & Francis
Following critical evaluation of the available literature to date, The International Society of
Sports Nutrition (ISSN) position regarding caffeine intake is as follows: Supplementation with …

The medicinal chemistry of caffeine

G Faudone, S Arifi, D Merk - Journal of Medicinal Chemistry, 2021 - ACS Publications
The purine alkaloid caffeine is the most widely consumed psychostimulant drug in the world
and has multiple beneficial pharmacological activities, for example, in neurodegenerative …

The neuroprotective effects of caffeine in neurodegenerative diseases

M Kolahdouzan, MJ Hamadeh - CNS neuroscience & …, 2017 - Wiley Online Library
Caffeine is the most widely used psychostimulant in Western countries, with antioxidant, anti‐
inflammatory and anti‐apoptotic properties. In Alzheimer's disease (AD), caffeine is …

Role of natural and synthetic compounds in modulating NRF2/KEAP1 signaling pathway in prostate cancer

G Tossetta, S Fantone, D Marzioni, R Mazzucchelli - Cancers, 2023 - mdpi.com
Simple Summary Several studies showed that oxidative stress is involved in cancer
occurrence, development, progression chemoresistance and radio resistance. The nuclear …

The methylation effect in medicinal chemistry

EJ Barreiro, AE Kümmerle, CAM Fraga - Chemical reviews, 2011 - ACS Publications
The monovalent methyl group is derived from methane through the removal of a hydrogen
atom, 1 and its etymology is directly related to the discovery of methanol. 2 The first reports …

Chronic cough: new insights and future prospects

A Morice, P Dicpinigaitis… - European …, 2021 - publications.ersnet.org
Chronic cough is defined in adults as a cough that lasts for≥ 8 weeks. When it proves
intractable to standard-of-care treatment, it can be referred to as refractory chronic cough …

International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors—an update

BB Fredholm, AP IJzerman, KA Jacobson… - Pharmacological …, 2011 - Elsevier
In the 10 years since our previous International Union of Basic and Clinical Pharmacology
report on the nomenclature and classification of adenosine receptors, no developments …

Actions of caffeine in the brain with special reference to factors that contribute to its widespread use

BB Fredholm, K Bättig, J Holmén… - Pharmacological …, 1999 - pharmrev.aspetjournals.org
Caffeine is the most widely consumed behaviorally active substance in the world. Almost all
caffeine comes from dietary sources (beverages and food), most of it from coffee and tea …

Receptors for purines and pyrimidines

V Ralevic, G Burnstock - Pharmacological reviews, 1998 - pharmrev.aspetjournals.org
Extracellular purines (adenosine, ADP, and ATP) and pyrimidines (UDP and UTP) are
important signaling molecules that mediate diverse biological effects via cellsurface …