Diabetes is an inflammatory disease: evidence from traditional Chinese medicines

W **e, L Du - Diabetes, obesity and metabolism, 2011 - Wiley Online Library
Diabetes is usually associated with inflammation. Inflammation contributes to the
development of diabetes. Traditional Chinese medicines (TCM) play an important role in …

Ophiopogon japonicus—A phytochemical, ethnomedicinal and pharmacological review

MH Chen, XJ Chen, M Wang, LG Lin… - Journal of …, 2016 - Elsevier
Abstract Ethnopharmacological relevance Ophiopogonis Radix (Maidong in Chinese), the
root of Ophiopogon japonicus, is widely used in local medicines of China, Japan and some …

Ruscogenin attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway

G Cao, N Jiang, Y Hu, Y Zhang, G Wang, M Yin… - International journal of …, 2016 - mdpi.com
Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, has been
shown to inhibit cerebral ischemic injury. However, its potential molecular action on blood …

Ruscogenin induces ferroptosis in pancreatic cancer cells

Z Song, X **ang, J Li, J Deng, Z Fang… - Oncology …, 2020 - spandidos-publications.com
Pancreatic cancer is characterized by aggressive and highly metastatic phenotypes. This
disease exhibits a poor patient prognosis and is considered a challenge due to the limited …

Ophiopogon japonicus and its active compounds: A review of potential anticancer effects and underlying mechanisms

Q Liu, JJ Lu, HJ Hong, Q Yang, Y Wang, XJ Chen - Phytomedicine, 2023 - Elsevier
Abstract Background Ophiopogon japonicus (Thunb.) Ker Gawl., a well-known Chinese
herb, has been used in traditional Chinese medicine for thousands of years. Extensive in …

[HTML][HTML] Antioxidant and anti-inflammatory medicinal plants have potential role in the treatment of cardiovascular disease: a review

P Adegbola, I Aderibigbe, W Hammed… - American journal of …, 2017 - ncbi.nlm.nih.gov
Cardiovascular disease is a compound name for clusters of disorders afflicting the heart and
blood vessels; it is assuming an increasing role as a major cause of morbidity and mortality …

Antimicrobial activities of endophytic fungi isolated from Ophiopogon japonicus (Liliaceae)

H Liang, Y **ng, J Chen, D Zhang, S Guo… - BMC complementary and …, 2012 - Springer
Background Drug resistance in bacteria has become a global concern and the search for
new antibacterial agents is urgent and ongoing. Endophytes provide an abundant reservoir …

Antinociceptive and anti-inflammatory activities of Aquilaria sinensis (Lour.) Gilg. Leaves extract

M Zhou, H Wang, J Kou, B Yu - Journal of ethnopharmacology, 2008 - Elsevier
AIM OF THE STUDY: The analgesic and anti-inflammatory activities of the ethanol extract of
Aquilaria sinensis (Lour.) Gilg. Leaves were observed in various experimental models …

Antitumor activity of bacterial exopolysaccharides from the endophyte Bacillus amyloliquefaciens sp. isolated from Ophiopogon japonicus

YT Chen, Q Yuan, LT Shan, MA Lin… - Oncology …, 2013 - spandidos-publications.com
The endophytic bacterium, MD-b1, was isolated from the medicinal plant Ophiopogon
japonicas and identified as the Bacillus amyloliquefaciens sp. with 99% similarity based on …

Ophiopogonin D, a steroidal glycoside abrogates STAT3 signaling cascade and exhibits anti-cancer activity by causing GSH/GSSG imbalance in lung carcinoma

JH Lee, C Kim, SG Lee, G Sethi, KS Ahn - Cancers, 2018 - mdpi.com
Natural medicinal plants are multi-targeted in nature and their anti-cancer activities are also
complex and varied, thus requiring a more systematic analysis of their modes of action …