Background Neuroinflammation with activation of microglia and production of
proinflammatory cytokines in the brain plays an active role in epileptic disorders. Brain …

Although many approaches to the therapy of epilepsy exist, most of antiepileptic drugs,
beside certain and unquestioned benefits, have convinced disadvantages. That is the …

Nigella sativa (NS) has been suggested to have neuroprotective and anti-seizures
properties. The aim of current study was to investigate the effects of NS hydro-alcoholic …

Regarding the therapeutic properties of Nigella sativa (NS), the effects of the plant hydro–
alcoholic extract on learning, memory and brain tissues oxidative damage were investigated …

A correlation between epilepsy and cellular redox imbalance has been suggested, although
the mechanism by which oxidative stress (OS) can be implicated in this disorder is not clear …

Albeit the pathogenesis of cognitive impairment after exposure to melamine has not been
fully elucidated, factors such as oxidative stress is thought to play potential roles. In the …

Background Menopause is associated with increased oxidative stress and memory
impairment. Based on the antioxidant property of ascorbic acid (AA), It's effect on cognitive …

Objective: Coriandrum sativum (C. sativum) as a medicinal plant has been pointed to have
analgesic, hypnotic and anti-oxidant effects. In the current study, a possible preventive effect …

Background: Indoleamine-2, 3-dioxygenase 1 (IDO1) is the initial and rate-limiting enzyme
in the metabolism of tryptophan (TRP) to kynurenine (KYN). IDO1-dependent neurotoxic …

Objective: Various morphological parts of pomegranate (Punica granatum L.) have
extensively been used in the folk medicine to treat an array of human ailments. The aim of …