Coding, or non-coding, that is the question
L Poliseno, M Lanza, PP Pandolfi - Cell Research, 2024 - nature.com
The advent of high-throughput sequencing uncovered that our genome is pervasively
transcribed into RNAs that are seemingly not translated into proteins. It was also found that …
transcribed into RNAs that are seemingly not translated into proteins. It was also found that …
Discovering the hidden function in fungal genomes
New molecular technologies have helped unveil previously unexplored facets of the
genome beyond the canonical proteome, including microproteins and short ORFs, products …
genome beyond the canonical proteome, including microproteins and short ORFs, products …
Chemically-inducible CRISPR/Cas9 circuits for ultra-high dynamic range gene perturbation
R Srinivasan, T Sun, A Sandles, D Wu, L Wang… - bioRxiv, 2024 - biorxiv.org
CRISPR/Cas9 technologies provide unique capabilities for modeling disease and
understanding gene-to-phenotype connections. In cultured cells, chemical-mediated control …
understanding gene-to-phenotype connections. In cultured cells, chemical-mediated control …