The divided bacterial genome: structure, function, and evolution
Approximately 10% of bacterial genomes are split between two or more large DNA
fragments, a genome architecture referred to as a multipartite genome. This multipartite …
fragments, a genome architecture referred to as a multipartite genome. This multipartite …
Old trade, new tricks: insights into the spontaneous mutation process from the partnering of classical mutation accumulation experiments with high-throughput …
Mutations spawn genetic variation which, in turn, fuels evolution. Hence, experimental
investigations into the rate and fitness effects of spontaneous mutations are central to the …
investigations into the rate and fitness effects of spontaneous mutations are central to the …
Prochlorococcus have low global mutation rate and small effective population size
Prochlorococcus are the most abundant free-living photosynthetic carbon-fixing organisms
in the ocean. Prochlorococcus show small genome sizes, low genomic G+ C content …
in the ocean. Prochlorococcus show small genome sizes, low genomic G+ C content …
In-host population dynamics of Mycobacterium tuberculosis complex during active disease
Tuberculosis (TB) is a leading cause of death globally. Understanding the population
dynamics of TB's causative agent Mycobacterium tuberculosis complex (Mtbc) in-host is vital …
dynamics of TB's causative agent Mycobacterium tuberculosis complex (Mtbc) in-host is vital …
A tale of genome compartmentalization: the evolution of virulence clusters in smut fungi
JY Dutheil, G Mannhaupt, G Schweizer… - Genome biology and …, 2016 - academic.oup.com
Smut fungi are plant pathogens mostly parasitizing wild species of grasses as well as
domesticated cereal crops. Genome analysis of several smut fungi including Ustilago …
domesticated cereal crops. Genome analysis of several smut fungi including Ustilago …
Sources of spontaneous mutagenesis in bacteria
JW Schroeder, P Yeesin, LA Simmons… - Critical reviews in …, 2018 - Taylor & Francis
Mutations in an organism's genome can arise spontaneously, that is, in the absence of
exogenous stress and prior to selection. Mutations are often neutral or deleterious to …
exogenous stress and prior to selection. Mutations are often neutral or deleterious to …
Long-term evolution of Burkholderia multivorans during a chronic cystic fibrosis infection reveals shifting forces of selection
Burkholderia multivorans is an opportunistic pathogen capable of causing severe disease in
patients with cystic fibrosis (CF). Patients may be chronically infected for years, during which …
patients with cystic fibrosis (CF). Patients may be chronically infected for years, during which …
Investigation of sequential outbreaks of Burkholderia cepacia and multidrug-resistant extended spectrum β-lactamase producing Klebsiella species in a West African …
Background Sick newborns admitted to neonatal units in low-resource settings are at an
increased risk of develo** hospital-acquired infections due to poor clinical care practices …
increased risk of develo** hospital-acquired infections due to poor clinical care practices …
Paramecium Genetics, Genomics, and Evolution
The ciliate genus Paramecium served as one of the first model systems in microbial
eukaryotic genetics, contributing much to the early understanding of phenomena as diverse …
eukaryotic genetics, contributing much to the early understanding of phenomena as diverse …
Codon usage and codon pair patterns in non-grass monocot genomes
Abstract Background and Aims Studies on codon usage in monocots have focused on
grasses, and observed patterns of this taxon were generalized to all monocot species. Here …
grasses, and observed patterns of this taxon were generalized to all monocot species. Here …