In human pathophysiology, the clash between microbial infection and host immunity
contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this …

Background Many nutrients have powerful immunomodulatory actions with the potential to
alter susceptibility to coronavirus disease 2019 (COVID-19) infection, progression to …

Paneth cells were first described in the late 19th century by Gustav Schwalbe and Josef
Paneth as columnar epithelial cells possessing prominent eosinophilic granules in their …

The first incidence of COVID-19 was reported in the Wuhan city of Hubei province in China
in late December 2019. Because of failure in timely closing of borders of the affected region …

Background: Vitamin D deficiency has been shown to be independently associated with
increased risk of viral acute respiratory infection (ARI) in a number of observational studies …

Over the last decade, the rapid emergence of multidrug-resistant pathogens has become a
global concern, which has prompted the search for alternative antibacterial agents for use in …

Repair of tissue wounds is a fundamental process to re‐establish tissue integrity and regular
function. Importantly, infection is a major factor that hinders wound healing. Multicellular …

The airway epithelium is now considered to be central to the orchestration of pulmonary
inflammatory and immune responses, and is also key to tissue remodelling. It acts as the first …

The human cathelicidin hCAP18/LL-37 has become a paradigm for the pleiotropic roles of
peptides in host defence. It has a remarkably wide functional repertoire that includes direct …

Cathelicidins are small, cationic, antimicrobial peptides found in humans and other species,
including farm animals (cattle, horses, pigs, sheep, goats, chickens, rabbits and in some …