A Concise Review of Synthetic Strategy, Mechanism of Action, and SAR Studies of Phthalazine Derivatives as Anticancer Agent
GC Arya, R Sharma, S Mehla - Letters in Drug Design & …, 2024 - benthamdirect.com
Background Colorectal cancer is the third foremost cause of death in women and men.
Globally, about 1.94 million colon cancer cases were diagnosed and around 0.93 million …
Globally, about 1.94 million colon cancer cases were diagnosed and around 0.93 million …
Facile synthesis, characterization, and antimicrobial evaluation of novel heterocycles, schiff bases, and N-nucleosides bearing phthalazine moiety
The present work describes convenient synthesis of the novel Schiff bases 5a and b by
reacting phthalazinones 4a and b with 4-methoxybenzaldehyde Reaction of the Schiff bases …
reacting phthalazinones 4a and b with 4-methoxybenzaldehyde Reaction of the Schiff bases …
Synthesis and Evaluation of Pyrido [2, 3‐d] pyrimidine and 1, 8‐Naphthyridine Derivatives as Potential Antitumor Agents
New series of pyrido [2, 3‐d] pyrimidine and 1, 8‐naphthyridine derivatives were
synthesized from 2‐amino‐6‐(phenoxathiin‐2‐yl)‐4‐(thiophene‐2‐yl) nicotinonitrile as …
synthesized from 2‐amino‐6‐(phenoxathiin‐2‐yl)‐4‐(thiophene‐2‐yl) nicotinonitrile as …
Synthesis of Novel Phthalazine Derivatives as Potential Anticancer and Antioxidant Agents Based on 1‐Chloro‐4‐(4‐phenoxyphenyl) phthalazine
A new series of phthalazine derivatives was synthesized from the reaction of 1‐chloro‐4‐(4‐
phenoxyphenyl) phthalazine as a reactive starting material with different carbon, nitrogen …
phenoxyphenyl) phthalazine as a reactive starting material with different carbon, nitrogen …
Cardanol-based green nanovesicles with antioxidant and cytotoxic activities
This manuscript describes the preparation of green nanovesicles by using cardanol as
renewable starting material with embedded minor amounts of phthalazines, a class of …
renewable starting material with embedded minor amounts of phthalazines, a class of …
Synthesis of novel phthalazine derivatives as pharmacological activities
Phthalazine derivatives attached to amino acid derivatives were synthesized with high
yields. The reaction of phthalazine derivatives with different phthalyl and tosylamino acids …
yields. The reaction of phthalazine derivatives with different phthalyl and tosylamino acids …
Sonogashira Reaction: Synthesis of Novel Derivatives of 3‐Aryl‐Substituted 6‐Chloroimidazo [2, 1‐a] phthalazines Catalyzed by Pd‐Cu in Water
M Bakherad, S Karami, A Keivanloo - ChemistrySelect, 2018 - Wiley Online Library
Abstract The reaction of 1‐chloro‐4‐propargylaminophthalazine with various aryl halides
catalyzed by Pd− Cu in the presence of potassium carbonate, as the base, in water leads to …
catalyzed by Pd− Cu in the presence of potassium carbonate, as the base, in water leads to …
Genotoxicity evaluation of a new phthalazine substituted β-lactam derivative in human lymphocytes
The aim of present study, to evaluate the genotoxic potential of 1-(4-(3, 3-dimethyl-1, 6-dioxo-
2, 3, 4, 6, 11, 13-hexahydro-1H-indazolo [1, 2b] phthalazine-13yl) phenyl)-2-phenylazetidine …
2, 3, 4, 6, 11, 13-hexahydro-1H-indazolo [1, 2b] phthalazine-13yl) phenyl)-2-phenylazetidine …
[PDF][PDF] Synthesis of novel series of phthalazine derivatives with antibacterial and antifungal evaluation
The oxirane derivative (2) was allowed to react with 4-amino benzoic acid to yield β-amino
derivative (3). The hydrazide (5) was reacted with glucose, aromatic aldehyde …
derivative (3). The hydrazide (5) was reacted with glucose, aromatic aldehyde …
[PDF][PDF] 1, 4-Disulfopiperazine-1, 4-diium chloride ([Piper-(SO3H) 2]. 2Cl) as an efficient ionic catalyst for synthesis of phthalazine derivatives
F Shirini, TG Koodehi, O Goli-Jolodar - Iranian Journal of Catalysis, 2017 - sid.ir
This article describe the applicability of 1, 4-disulfopiperazine-1, 4-diium chloride ([Piper-
(SO3H) 2]. 2Cl) as a green, versatile and Brönsted acidic ionic catalyst in the promotion of …
(SO3H) 2]. 2Cl) as a green, versatile and Brönsted acidic ionic catalyst in the promotion of …