mRNA vaccines for infectious diseases: principles, delivery and clinical translation
N Chaudhary, D Weissman… - Nature reviews Drug …, 2021 - nature.com
Over the past several decades, messenger RNA (mRNA) vaccines have progressed from a
scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the …
scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the …
Advances in COVID-19 mRNA vaccine development
E Fang, X Liu, M Li, Z Zhang, L Song, B Zhu… - Signal transduction and …, 2022 - nature.com
To date, the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …
Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems
New achievements in the realm of nanoscience and innovative techniques of nanomedicine
have moved micro/nanoparticles (MNPs) to the point of becoming actually useful for …
have moved micro/nanoparticles (MNPs) to the point of becoming actually useful for …
mRNA vaccine for cancer immunotherapy
Abstract mRNA vaccines have become a promising platform for cancer immunotherapy.
During vaccination, naked or vehicle loaded mRNA vaccines efficiently express tumor …
During vaccination, naked or vehicle loaded mRNA vaccines efficiently express tumor …
Self-assembled peptide-based nanostructures: Smart nanomaterials toward targeted drug delivery
Self-assembly of peptides can yield an array of well-defined nanostructures that are highly
attractive nanomaterials for many biomedical applications such as drug delivery. Some of …
attractive nanomaterials for many biomedical applications such as drug delivery. Some of …
Ongoing clinical trials of nonviral siRNA therapeutics
Short interfering RNAs (siRNA) are a powerful class of genetic medicines whose clinical
translation can be hindered by their suboptimal delivery properties in vivo. Here, we provide …
translation can be hindered by their suboptimal delivery properties in vivo. Here, we provide …
Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications
CD Spicer, C Jumeaux, B Gupta… - Chemical Society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …
Formulation and delivery technologies for mRNA vaccines
Abstract mRNA vaccines have become a versatile technology for the prevention of infectious
diseases and the treatment of cancers. In the vaccination process, mRNA formulation and …
diseases and the treatment of cancers. In the vaccination process, mRNA formulation and …
Synthetic materials at the forefront of gene delivery
I Lostalé-Seijo, J Montenegro - Nature Reviews Chemistry, 2018 - nature.com
The delivery of nucleic acids with transient activity for genetic engineering is a promising
methodology with potential applications in the treatment of diseases ranging from cancer …
methodology with potential applications in the treatment of diseases ranging from cancer …
[HTML][HTML] Recent approaches for enhancing the performance of dissolving microneedles in drug delivery applications
Dissolving microneedles (dMNs) are promising versatile drug delivery systems for the
transdermal delivery of numerous drugs, enabling their use in a wide range of biomedical …
transdermal delivery of numerous drugs, enabling their use in a wide range of biomedical …