Despite efficient combination of the antiretroviral therapy (cART), which significantly
decreased mortality and morbidity of HIV-1 infection, a definitive HIV cure has not been …

HIV-associated neurological disorders (HAND) affect up to 50% of people living with HIV
(PLWH), even in the era of combination antiretroviral therapy (cART). HIV-DNA can be …

By binding to multiple antigens simultaneously, multispecific antibodies are expected to
substantially improve both the activity and long-term efficacy of antibody-based …

HIV-1 eradication is hindered by viral persistence in cell reservoirs, established not only in
circulatory CD4+ T-cells but also in tissue-resident macrophages. The nature of macrophage …

The male genital tract (MGT) is the target of a number of viral infections that can have
deleterious consequences at the individual, offspring, and population levels. These …

Macrophages are essential for HIV-1 pathogenesis and represent major viral reservoirs.
Therefore, it is critical to understand macrophage infection, especially in tissue …

Although cells of the myeloid lineages, including tissue macrophages and conventional
dendritic cells, were rapidly recognized, in addition to CD4+ T lymphocytes, as target cells of …

People with HIV (PWH) are at elevated risk for cardiovascular diseases (CVDs), including
myocardial infarction, heart failure, and sudden cardiac death, among other CVD …

The most studied HIV eradication approach is the “shock and kill” strategy, which aims to
reactivate the latent reservoir by latency reversing agents (LRAs) and allowing elimination of …

The usage of antiretroviral treatment (ART) has considerably decreased the morbidity and
mortality related to HIV-1 (human immunodeficiency virus type 1) infection. However, ART is …