Anxiety disorders are the most common mental disorders and are often chronic and
disabling. Although exposure-based treatments are effective, a substantial number of …

The Hierarchical Taxonomy of Psychopathology (HiTOP) is a quantitative nosological
system that addresses shortcomings of traditional mental disorder diagnoses, including …

Objective: Anxiety disorders are common and often disabling. The goal of this study was to
examine the genetic architecture of anxiety disorders and anxiety symptoms, which are also …

Depression and anxiety are highly prevalent and comorbid psychiatric traits that cause
considerable burden worldwide. Here we use factor analysis and genomic structural …

Several labels, such as neuroticism, negative emotionality, and dispositional negativity,
indicate a broad dimension of psychopathology. However, largely separate, often disorder …

Neuroticism--the tendency to experience negative emotions, along with the perception that
the world is filled with stressful, unmanageable challenges--is strongly associated with …

Dispositional negativity—the propensity to experience and express more frequent, intense,
or enduring negative affect—is a fundamental dimension of childhood temperament and …

When extreme, anxiety can become debilitating. Anxiety disorders, which often first emerge
early in development, are common and challenging to treat, yet the underlying mechanisms …

Research across age groups has consistently indicated that psychopathology has a general
factor structure such that a broad latent dimension (or p factor) captures variance common to …

Psychiatric research is still strongly influenced by its major classification schemes, the DSM-
5 (1) and ICD-10 (2). According to these diagnostic classification systems, psychiatric …