Advancements in nanoparticle-based treatment approaches for skin cancer therapy

L Zeng, BHJ Gowda, MG Ahmed, MAS Abourehab… - Molecular Cancer, 2023‏ - Springer
Skin cancer has emerged as the fifth most commonly reported cancer in the world, causing a
burden on global health and the economy. The enormously rising environmental changes …

Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?

M Vallet-Regí, F Schüth, D Lozano, M Colilla… - Chemical Society …, 2022‏ - pubs.rsc.org
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …

Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024‏ - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Cancer nanomedicine toward clinical translation: Obstacles, opportunities, and future prospects

P Zhang, Y **ao, X Sun, X Lin, S Koo, AV Yaremenko… - Med, 2023‏ - cell.com
With the integration of nanotechnology into the medical field at large, great strides have
been made in the development of nanomedicines for tackling different diseases, including …

[HTML][HTML] Nanotechnology-based delivery of CRISPR/Cas9 for cancer treatment

X Xu, C Liu, Y Wang, O Koivisto, J Zhou, Y Shu… - Advanced drug delivery …, 2021‏ - Elsevier
Abstract CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats-
associated protein 9) is a potent technology for gene-editing. Owing to its high specificity …

[HTML][HTML] In vivo delivery of CRISPR-Cas9 therapeutics: Progress and challenges

M Behr, J Zhou, B Xu, H Zhang - Acta Pharmaceutica Sinica B, 2021‏ - Elsevier
Within less than a decade since its inception, CRISPR-Cas9-based genome editing has
been rapidly advanced to human clinical trials in multiple disease areas. Although it is highly …

Recent trends in cancer therapy: A review on the current state of gene delivery

EB Yahya, AM Alqadhi - Life Sciences, 2021‏ - Elsevier
Cancer treatment has been always considered one of the most critical and vital themes of
clinical issues. Many approaches have been developed, depending on the type and the …

Reprogramming the Tumor Microenvironment through Second‐Near‐Infrared‐Window Photothermal Genome Editing of PD‐L1 Mediated by Supramolecular Gold …

H Tang, X Xu, Y Chen, H **n, T Wan, B Li… - Advanced …, 2021‏ - Wiley Online Library
A photothermal genome‐editing strategy is described to improve immune checkpoint
blockade (ICB) therapy by CRISPR/Cas9‐mediated disruption of PD‐L1 and mild …

[HTML][HTML] Novel tumor-targeting nanoparticles for cancer treatment—A review

AG Niculescu, AM Grumezescu - International Journal of Molecular …, 2022‏ - mdpi.com
Being one of the leading causes of death and disability worldwide, cancer represents an
ongoing interdisciplinary challenge for the scientific community. As currently used treatments …

Delivery of nucleic acid based genome editing platforms via lipid nanoparticles: clinical applications

R Masarwy, L Stotsky-Oterin, A Elisha… - Advanced drug delivery …, 2024‏ - Elsevier
CRISPR/Cas technology presents a promising approach for treating a wide range of
diseases, including cancer and genetic disorders. Despite its potential, the translation of …