Medical micro/nanorobots in precision medicine

F Soto, J Wang, R Ahmed, U Demirci - Advanced science, 2020 - Wiley Online Library
Advances in medical robots promise to improve modern medicine and the quality of life.
Miniaturization of these robotic platforms has led to numerous applications that leverages …

Microfluidics for sperm analysis and selection

R Nosrati, PJ Graham, B Zhang, J Riordon… - Nature Reviews …, 2017 - nature.com
Infertility is a growing global health issue with far-reaching socioeconomic implications. A
downward trend in male fertility highlights the acute need for affordable and accessible …

Microfluidic sorting selects sperm for clinical use with reduced DNA damage compared to density gradient centrifugation with swim-up in split semen samples

MM Quinn, L Jalalian, S Ribeiro, K Ona… - Human …, 2018 - academic.oup.com
STUDY QUESTION Does microfluidic sorting improve the selection of sperm with lower DNA
fragmentation over standard density-gradient centrifugation? SUMMARY ANSWER …

Two-dimensional slither swimming of sperm within a micrometre of a surface

R Nosrati, A Driouchi, CM Yip, D Sinton - Nature communications, 2015 - nature.com
Sperm motion near surfaces plays a crucial role in fertilization, but the nature of this motion
has not been resolved. Using total internal reflection fluorescence microscopy, we …

Simulating nature in sperm selection for assisted reproduction

ETY Leung, CL Lee, X Tian, KKW Lam, RHW Li… - Nature Reviews …, 2022 - nature.com
Sperm selection in the female reproductive tract (FRT) is sophisticated. Only about 1,000
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …

Sperm cell driven microrobots—emerging opportunities and challenges for biologically inspired robotic design

AV Singh, MHD Ansari, M Mahajan, S Srivastava… - Micromachines, 2020 - mdpi.com
With the advent of small-scale robotics, several exciting new applications like Targeted Drug
Delivery, single cell manipulation and so forth, are being discussed. However, some …

Review of the applications of micro/nanorobots in biomedicine

H Zhang, J Tang, H Cao, C Wang… - ACS Applied Nano …, 2024 - ACS Publications
The advancement of precision medicine in modern biomedicine has been significantly
propelled by the emergence of micro/nanorobots. The combination of micro/nanorobots and …

Rapid selection of sperm with high DNA integrity

R Nosrati, M Vollmer, L Eamer, MC San Gabriel… - Lab on a Chip, 2014 - pubs.rsc.org
Sperm selection is essential to assisted reproductive technology (ART), influencing
treatment outcomes and the health of offspring. The fundamental challenge of sperm …

Selection of functional human sperm with higher DNA integrity and fewer reactive oxygen species

W Asghar, V Velasco, JL Kingsley… - Advanced …, 2014 - Wiley Online Library
Fertilization and reproduction are central to the survival and propagation of a species.
Couples who cannot reproduce naturally have to undergo in vitro clinical procedures. An …

Sperm selection methods in the 21st century

DA Vaughan, D Sakkas - Biology of reproduction, 2019 - academic.oup.com
Natural sperm selection in humans is a rigorous process resulting in the highest quality
sperm reaching, and having an opportunity to fertilize, the oocyte. Relative to other …