The diagnosis and treatment of patients with mendelian susceptibility to mycobacterial
disease (MSMD) pose consistent challenges due to the diverse infection spectrum observed …

Detection of changes in phosphorylation of cell signaling molecules using flow cytometry is
termed “phosphoflow” or “phospho-flow cytometry”. Phosphoflow has wide application for …

Inborn errors of immunity (IEI) are genetic disorders with extensive clinical presentations.
They can range from increased susceptibility to infections to significant immune …

Background Post-vaccination BCG disease typically attests to underlying inborn errors of
immunity (IEIs), with the highest rates of complications in patients with Mendelian …

Background The recurrence of tuberculosis (TB) continues to place a significant burden on
patients and TB programs worldwide. Repeated TB episodes can develop either due to …

Background: The recurrence of tuberculosis (TB) continues to place a significant burden on
patients and TB programs worldwide. Repeated TB episodes can develop either due to …

Abstract Mendelian Susceptibility to Mycobacterial Disease (MSMD) is a rare primary
immunodeficiency characterized by increased susceptibility to infections caused by weakly …

Abstract Mendelian Susceptibility to Mycobacterial Disease (MSMD) is a rare primary
immunodeficiency characterized by increased susceptibility to infections caused by weakly …

Inborn errors of immunity (IEI) represent a diverse group of disorders resulting from
monogenic defects in immune system genes. These defects cause individuals to be more …

Objective: Mendelian susceptibility to mycobacterial disease (MSMD) is a subgroup of
primary immunodeficiencies which develops with the Bacille Calmette–Guérin (BCG) …