In this review we will describe eight commonly used rat brain tumor models and their
application for the development of novel therapeutic and diagnostic modalities. The C6, 9L …

Microbeam radiation therapy (MRT) uses highly collimated, quasi-parallel arrays of X-ray
microbeams of 50–600keV, produced by third generation synchrotron sources, such as the …

Ultrasmall gadolinium-based nanoparticles (GBNs) induce both a positive contrast for
magnetic resonance imaging and a radiosentizing effect. The exploitation of these …

Purpose: This Monte Carlo simulation work aims at studying a new radiotherapy approach
called proton‐minibeam radiation therapy (pMBRT). The main objective of this proof of …

Synchrotron facilities produce ultra-high dose rate X-rays that can be used for selective
cancer treatment when combined with micron-sized beams. Synchrotron microbeam …

After years of lethargy, studies on two non-conventional microstructures in time and space of
the beams used in radiation therapy are enjoying a huge revival. The first effect called …

Microbeam radiation therapy (MRT) is a new form of preclinical radiotherapy using quasi-
parallel arrays of synchrotron X-ray microbeams. While the deposition of several hundred …

Owing to the high atomic number (Z) of gold element, the gold nanoparticles appear as very
promising radiosensitizing agents. This character can be exploited for improving the …

Purpose Synchrotron microbeam radiation therapy (MRT) is based on the spatial
fractionation of the incident, highly focused synchrotron beam into arrays of parallel …

To analyze the effects of the microbeam width (25, 50 and 75 µm) on the survival of 9L
gliosarcoma tumor-bearing rats and on toxicity in normal tissues in normal rats after …