Pharmacological properties and molecular mechanisms of thymol: prospects for its therapeutic potential and pharmaceutical development

MF Nagoor Meeran, H Javed, H Al Taee… - Frontiers in …, 2017 - frontiersin.org
Thymol, chemically known as 2-isopropyl-5-methylphenol is a colorless crystalline
monoterpene phenol. It is one of the most important dietary constituents in thyme species …

Oxidative stress, eryptosis and anemia: a pivotal mechanistic nexus in systemic diseases

R Bissinger, AAM Bhuyan, SM Qadri… - The FEBS …, 2019 - Wiley Online Library
The average lifespan of circulating erythrocytes usually exceeds hundred days. Prior to that,
however, erythrocytes may be exposed to oxidative stress in the circulation which could …

Extraction of astaxanthin from Haematococcus pluvialis with hydrophobic deep eutectic solvents based on oleic acid

W Pitacco, C Samorì, L Pezzolesi, V Gori, A Grillo… - Food Chemistry, 2022 - Elsevier
Three novel hydrophobic deep eutectic solvents (DESs) based on oleic acid and terpenes
(thymol, dl-menthol, and geraniol) were prepared, characterized, and used to extract …

Effects of oregano, carvacrol and thymol on Staphylococcus aureus and Staphylococcus epidermidis biofilms

A Nostro, AS Roccaro, G Bisignano… - Journal of medical …, 2007 - microbiologyresearch.org
The aim of this study was to evaluate the effect of oregano essential oil, carvacrol and thymol
on biofilm-grown Staphylococcus aureus and Staphylococcus epidermidis strains, as well as …

Antioxidant properties of Thymus vulgaris oil against aflatoxin-induce oxidative stress in male rats

AA El-Nekeety, SR Mohamed, AS Hathout, NS Hassan… - Toxicon, 2011 - Elsevier
The leafy parts of thyme and its essential oil have been used in foods for the flavor, aroma
and preservation and also in folk medicines. The aim of the current study was to determine …

Synthesis and antioxidant activity of thymol and carvacrol based Schiff bases

D Kumar, DS Rawat - Bioorganic & medicinal chemistry letters, 2013 - Elsevier
Thymol and carvacrol are well known antioxidants found in the extract of the plants of thyme
species. The Schiff bases of 2-iso-propyl-5-methyl-phenol (thymol/1a), 2-tert-butyl-5-methyl …

Bioactivity of essential oils and their components

AR Koroch, H Rodolfo Juliani, JA Zygadlo - Flavours and fragrances …, 2007 - Springer
5.10 Conclusions The present review demonstrates that EOs and their components have
many functional properties and exert their action in mammals as well as in other organisms …

Influence of p-coumaric acid on doxorubicin-induced oxidative stress in rat's heart

MH Abdel-Wahab, MA El-Mahdy, MF Abd-Ellah… - Pharmacological …, 2003 - Elsevier
The therapeutic value of doxorubicin (DOX) as anticancer antibiotic is limited by its
cardiotoxicity. The implication of natural phenolic acids in the prevention of many pathologic …

Andrographolide: A natural product template for the generation of structurally and biologically diverse diterpenes

SGS Kandanur, N Tamang, NR Golakoti… - European Journal of …, 2019 - Elsevier
From times immemorial, natural products have played an important role in the management
of human health. Andrographis paniculata, belonging to the family Acanthaceae and its …

Thymol and carvacrol prevent doxorubicin‐induced cardiotoxicity by abrogation of oxidative stress, inflammation, and apoptosis in rats

ESM El‐Sayed, AM Mansour… - … of biochemical and …, 2016 - Wiley Online Library
The aim of this study was to assess the possible protective effects of thymol and carvacrol
(CAR) against doxorubicin (DOX)‐induced cardiotoxicity. A single dose of DOX (10 mg/kg iv) …