Published data on the main approaches to the formation of the heterocyclic 2-
aminopyrimidine system, which is one of important pharmacophores responsible for the …

A pyrimido [4, 5-d] pyrimidine featuring the hydrogen bond donors and acceptors of both
guanine (G) and cytosine (C) in the appropriate geometry undergoes hierarchical self …

Purpose This work presents the preparation of a nanocomposite of ampicillin-conjugated
gold nanoparticles (AuNPs) and self-assembled rosette nanotubes (RNTs), and evaluates …

The human histamine H4 receptor (hH4R) is a promising new target in the therapy of
inflammatory diseases and disorders of the immune system. For the development of new …

The present work reports the synthesis of three new nitrogen-containing heteronuclear
molecules (two pyrimidines and one pyrrolopyrimidine). Based on the 12 principles of green …

The review summarizes literature data on the methods of synthesis of o-aminopyrimidine
aldehydes and o-aminopyrimidine ketones and their application for the construction of fused …

A new self-assembling tricyclic module (× K1) featuring the Watson− Crick H-bonding arrays
of guanine and cytosine fused to an internal pyridine ring was synthesized. When dissolved …

Rosette nanotubes (RNTs) are a class of materials formed by molecular self-assembly of a
fused guanine–cytosine base (G∧ C base). An important feature of these self-assembled …

Two efficient asymmetric routes to γ-secretase modulator BMS-932481, under investigation
for Alzheimer's disease, have been developed. The key step for the first route involves a …

Inspired from biological systems, small synthetic organic molecules expressing the
hydrogen bonding arrays of the DNA bases guanine and cytosine were prepared, and their …