Humans and animals lose tissues and organs due to congenital defects, trauma, and
diseases. The human body has a low regenerative potential as opposed to the urodele …

Many natural products present in our diet, including flavonoids, can prevent the progression
of cancer and other diseases. Resveratrol, a natural polyphenol present in various fruits and …

Abstract Silent information regulator 1 (SIRT1), a highly conserved NAD+-dependent
deacetylase, is a cellular regulator that has received extensive attention in recent years and …

Osteoarthritis (OA) is one of the progressing chronic joint associated with by many complex
factors such as age, obesity, and trauma. Knee osteoarthritis (KOA) is the most common type …

Abstract Context Polygonum cuspidatum Sieb. et Zucc (Polygonaceae), the root of which is
included in the Chinese Pharmcopoeia under the name 'Huzhang', has a long history as a …

The most abundant protein found in mammals is collagen, and there are around 28 different
types of collagen found in the human body, but there are five types, namely, Type I, Type II …

Atopic dermatitis (AD) is a chronic inflammatory skin disease caused by the dysregulation of
cytokines and other immune mediators. JAK/STAT is a classical signal transduction pathway …

Cartilage tissue engineering is an emerging technique for the regeneration of cartilage
tissue damaged as a result of trauma or disease. As the propensity for healing and …

It is estimated that by 2023, approximately 20% of the population of Western Europe and
North America will suffer from a degenerative joint disease commonly known as …

Osteoarthritis (OA) is a chronic degenerative disease caused by various factors such as
aging, obesity, trauma, and genetics. It is a challenging condition faced by orthopedic …