Many environmental conditions can constrain the ability of animals to obtain sufficient food
energy, or transform that food energy into useful chemical forms. To survive extended …

Endothermic mammals and birds require intensive energy turnover to sustain high body
temperatures and metabolic rates. To cope with the energetic bottlenecks associated with …

Hibernation evolved in some small mammals that live in cold environments, presumably to
conserve energy when food supplies are low. Throughout the winter, hibernators cycle …

Fluctuations in oxygen (O2) concentrations represent a major challenge to aerobic
organisms and can be extremely damaging to their mitochondria. Marine intertidal molluscs …

Barth syndrome is a complex metabolic disorder caused by mutations in the mitochondrial
transacylase tafazzin. Recently, an inducible tafazzin shRNA knockdown mouse model was …

During hibernation, animals cycle between periods of torpor, during which body temperature
(Tb) and metabolic rate (MR) are suppressed for days, and interbout euthermia (IBE), during …

Processes acting at the level of the mitochondria have been suggested to affect the thermal
limits of organisms. To determine whether changes in mitochondrial properties could …

Hibernation and daily torpor involve substantial decreases in body temperature and
metabolic rate, allowing birds and mammals to cope with cold environments and/or limited …

Intertidal bivalves are commonly exposed to multiple stressors including periodic hypoxia,
temperature fluctuations and pollution, which can strongly affect energy metabolism. We …

For long-duration manned space missions to Mars and beyond, reduction of astronaut
metabolism by torpor, the metabolic state during hibernation of animals, would be a game …