Metal–organic frameworks (MOFs) as apt luminescent probes for the detection of biochemical analytes

D Luo, J Huang, Y Jian, A Singh, A Kumar… - Journal of Materials …, 2023 - pubs.rsc.org
The detection of active substances in the body is very important for good human health as it
gives important insights into the smooth functioning of the body. Most of the conventional …

Advances in multiplexed techniques for the detection and quantification of microRNAs

T Jet, G Gines, Y Rondelez, V Taly - Chemical Society Reviews, 2021 - pubs.rsc.org
MicroRNA detection is currently a crucial analytical chemistry challenge: almost 2000
papers were referenced in PubMed in 2018 and 2019 for the keywords “miRNA detection …

MicroRNA: function, detection, and bioanalysis

H Dong, J Lei, L Ding, Y Wen, H Ju, X Zhang - Chemical reviews, 2013 - ACS Publications
Mature microRNAs (miRNAs) are a class of evolutionally conserved, single-stranded, small
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …

Rolling circular amplification (RCA)-assisted CRISPR/Cas9 cleavage (RACE) for highly specific detection of multiple extracellular vesicle MicroRNAs

R Wang, X Zhao, X Chen, X Qiu, G Qing… - Analytical …, 2019 - ACS Publications
Multiplexed detection of extracellular vesicle (EV)-derived microRNAs (miRNAs) plays a
critical role in facilitating disease diagnosis and prognosis evaluation. Herein, we developed …

MicroRNA profiling: approaches and considerations

CC Pritchard, HH Cheng, M Tewari - Nature Reviews Genetics, 2012 - nature.com
MicroRNAs (miRNAs) are small RNAs that post-transcriptionally regulate the expression of
thousands of genes in a broad range of organisms in both normal physiological contexts …

Circulating miRNA analysis for cancer diagnostics and therapy

L Valihrach, P Androvic, M Kubista - Molecular Aspects of Medicine, 2020 - Elsevier
Successful treatment of cancer depends on early diagnosis and effective monitoring of
patients' response to therapy. Traditional tools based on tumor biopsies lack the sensitivity …

Signal amplification in living cells: a review of microRNA detection and imaging

H Peng, AM Newbigging, MS Reid, JS Uppal… - Analytical …, 2019 - ACS Publications
MicroRNA (miRNA) is a class of endogenous, noncoding RNA with a typical length of 19−
23 nucleotides (nt). 1− 3 miRNA regulate the expression of specific genes by binding to …

[HTML][HTML] MicroRNA amplification and detection technologies: opportunities and challenges for point of care diagnostics

VP Dave, TA Ngo, AK Pernestig, D Tilevik, K Kant… - Laboratory …, 2019 - Elsevier
The volume of point of care (POC) testing continues to grow steadily due to the increased
availability of easy-to-use devices, thus making it possible to deliver less costly care closer …

Systematic comparison of microarray profiling, real-time PCR, and next-generation sequencing technologies for measuring differential microRNA expression

A Git, H Dvinge, M Salmon-Divon, M Osborne, C Kutter… - Rna, 2010 - rnajournal.cshlp.org
RNA abundance and DNA copy number are routinely measured in high-throughput using
microarray and next-generation sequencing (NGS) technologies, and the attributes of …

The art of microRNA research

E Van Rooij - Circulation research, 2011 - Am Heart Assoc
Originally identified as moderate biological modifiers, microRNAs have recently emerged as
powerful regulators of diverse cellular processes with especially important roles in disease …