The proposal of a double‐helical structure for DNA over 60 years ago provided an eminently
satisfying explanation for the heritability of genetic information. But why is DNA, and not …

It has been more than 50 years since the elucidation of the structure of double-helical DNA.
Despite active research and progress in DNA biology and biochemistry, much remains to be …

The utility of molecular dynamics (MD) simulations to model biomolecular structure,
dynamics, and interactions has witnessed enormous advances in recent years due to the …

We describe Curves+, a new nucleic acid conformational analysis program which is
applicable to a wide range of nucleic acid structures, including those with up to four strands …

We explore in detail the structural, mechanical, and thermodynamic properties of a coarse-
grained model of DNA similar to that recently introduced in a study of DNA nanotweezers …

By regulating access to the genetic code, DNA supercoiling strongly affects DNA
metabolism. Despite its importance, however, much about supercoiled DNA (positively …

Coarse-grained (CG) modeling approaches are widely used to simulate many important
biological processes involving DNA, including chromatin folding and genomic packaging …

Although DNA is frequently bent and supercoiled in the cell, much of the available
information on DNA structure at the atomistic level is restricted to short linear sequences. We …

As a key molecule of life, Deoxyribo-Nucleic Acid (DNA) is the focus of numbers of
investigations with the help of biological, chemical and physical techniques. From a physical …

Over the past ten years, the all-atom molecular dynamics method has grown in the scale of
both systems and processes amenable to it and in its ability to make quantitative predictions …