Aerosol drug delivery: developments in device design and clinical use

MB Dolovich, R Dhand - The Lancet, 2011‏ - thelancet.com
Aerosolised drugs are prescribed for use in a range of inhaler devices and systems.
Delivering drugs by inhalation requires a formulation that can be successfully aerosolised …

Current evidence for the effectiveness of heated and humidified high flow nasal cannula supportive therapy in adult patients with respiratory failure

O Roca, G Hernández, S Díaz-Lobato, JM Carratalá… - Critical care, 2016‏ - Springer
High flow nasal cannula (HFNC) supportive therapy has emerged as a safe, useful therapy
in patients with respiratory failure, improving oxygenation and comfort. Recently several …

High-flow nasal cannula: recommendations for daily practice in pediatrics

C Milési, M Boubal, A Jacquot, J Baleine… - Annals of intensive …, 2014‏ - Springer
High-flow nasal cannula (HFNC) is a relatively new device for respiratory support. In
pediatrics, HFNC use continues to increase as the system is easily set up and is well …

Nasal high flow in management of children with status asthmaticus: a retrospective observational study

F Baudin, A Buisson, B Vanel, B Massenavette… - Annals of Intensive …, 2017‏ - Springer
Background Asthma is the most common obstructive airway disease in children and adults.
Nasal high flow (NHF) is a recent device that is now used as a primary support for …

Nasal high flow nebulization in infants and toddlers: an in vitro and in vivo scintigraphic study

F Réminiac, L Vecellio, RM Loughlin… - Pediatric …, 2017‏ - Wiley Online Library
Aerosol therapy in infants and toddlers is challenging. Nebulization within a nasal high flow
(NHF) circuit is attractive. The aim of this study was to quantify aerosol lung deposition when …

Aerosol therapy in adults receiving high flow nasal cannula oxygen therapy

F Réminiac, L Vecellio, N Heuzé-Vourc'h… - Journal of aerosol …, 2016‏ - liebertpub.com
Background: High flow nasal cannula oxygen therapy (HFT) is increasingly used in intensive
and emergency care departments. Patients suffering from respiratory failure, who are likely …

Aerosol therapy during noninvasive ventilation or high-flow nasal cannula

DR Hess - Respiratory care, 2015‏ - rc.rcjournal.com
Noninvasive ventilation (NIV) and high-flow nasal cannula (HFNC) are increasingly used for
patients with acute respiratory failure. Some patients receiving these therapies might also …

[HTML][HTML] Clinical controversies in aerosol therapy for infants and children

RM DiBlasi - Respiratory Care, 2015‏ - liebertpub.com
Pediatric patients are different from adult patients with respect to airway anatomy and
breathing patterns. They are also incapable of following commands and often reject …

Influences of cannula size and flow rate on aerosol drug delivery through the Vapotherm humidified high-flow nasal cannula system

SA Perry, KC Kesser, DE Geller… - Pediatric Critical Care …, 2013‏ - journals.lww.com
Objective: We investigated the in vitro inspired dose and particle size distribution of albuterol
delivered by a vibrating mesh nebulizer through the Vapotherm (Stevensville, MD) …

Devices for improved delivery of nebulized pharmaceutical aerosols to the lungs

W Longest, B Spence, M Hindle - Journal of aerosol medicine and …, 2019‏ - liebertpub.com
Nebulizers have a number of advantages for the delivery of inhaled pharmaceutical
aerosols, including the use of aqueous formulations and the ability to deliver process …