Wnt/β-catenin signaling, a highly conserved pathway through evolution, regulates key
cellular functions including proliferation, differentiation, migration, genetic stability …

Increased dietary fiber consumption has been associated with many beneficial effects,
including amelioration of obesity and insulin resistance. These effects may be due to the …

Secondary bile acids (BAs) and short chain fatty acids (SCFAs), two major types of bacterial
metabolites in the colon, cause opposing effects on colonic inflammation at chronically high …

The Wnt/β-catenin signaling pathway exerts integral roles in embryogenesis and adult
homeostasis. Aberrant activation of the pathway is implicated in growth-associated diseases …

The evolutionarily conserved Wnt signaling pathway plays essential roles during embryonic
development and tissue homeostasis. Notably, comprehensive genetic studies in …

WNTs and their downstream effectors regulate proliferation, death, and migration and cell
fate decision. Deregulation of WNT signaling is associated with various cancers including …

Many epidemiological and experimental studies have suggested that dietary fiber plays an
important role in colon cancer prevention. These findings may relate to the ability of fiber to …

The microbial community populating the human digestive tract has been linked to the
development of obesity, diabetes and liver diseases. Proposed mechanisms on how the gut …

Recent studies have been considered to symbiotic interactions of the human gastrointestinal
microbiota and human lifestyle-related disorders. The human gastrointestinal microbiota …

Colorectal cancer (CRC) is one of the most common carcinomas. Although great progress
has been made in recent years, CRC survival remains unsatisfactory due to high metastasis …