The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …

Short peptides are ubiquitous in nature. They are found as hormones, pheromones,
antibacterial and antifungal agents in innate immunity systems, toxins, and pesticides. But …

Polymers, ceramics and metals have historically dominated the application of materials in
medicine. Yet rationally designed materials that exploit specific, directional, tunable and …

The radical response of peripheral nerves to injury (Wallerian degeneration) is the
cornerstone of nerve repair. We show that activation of the transcription factor c-Jun in …

Organic materials naturally lend themselves to the crafting of structure and function using the
strategies of self-assembly and supramolecular chemistry employed so effectively by …

This review discusses supramolecular biofunctional materials, a novel class of biomaterials
formed by small molecules that are held together via noncovalent interactions. The …

Biomaterials made from self-assembling, short peptides and peptide derivatives have great
potential to generate powerful new therapies in regenerative medicine. The high signaling …

Amphiphilic molecules, comprising hydrophobic and hydrophilic moieties and the intrinsic
propensity to self‐assemble in aqueous environment, sustain a fascinating spectrum of …

Biomimetic scaffolds mimic important features of the extracellular matrix (ECM) architecture
and can be finely controlled at the nano‐or microscale for tissue engineering. Rational …

Hydrogel materials have been employed as biological scaffolds for tissue regeneration
across a wide range of applications. Their versatility and biomimetic properties make them …