Phages and the evolution of bacterial pathogens: from genomic rearrangements to lysogenic conversion
H Brüssow, C Canchaya… - … and molecular biology …, 2004 - Am Soc Microbiol
Comparative genomics demonstrated that the chromosomes from bacteria and their viruses
(bacteriophages) are coevolving. This process is most evident for bacterial pathogens where …
(bacteriophages) are coevolving. This process is most evident for bacterial pathogens where …
Comparative genomics: the bacterial pan-genome
Bacterial genome sequencing has become so easy and accessible that the genomes of
multiple strains of more and more individual species have been and will be generated …
multiple strains of more and more individual species have been and will be generated …
Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: Implications for the microbial “pan-genome”
H Tettelin, V Masignani… - Proceedings of the …, 2005 - National Acad Sciences
The development of efficient and inexpensive genome sequencing methods has
revolutionized the study of human bacterial pathogens and improved vaccine design …
revolutionized the study of human bacterial pathogens and improved vaccine design …
Streptococcus Adherence and Colonization
AH Nobbs, RJ Lamont… - … and molecular biology …, 2009 - Am Soc Microbiol
Streptococci readily colonize mucosal tissues in the nasopharynx; the respiratory,
gastrointestinal, and genitourinary tracts; and the skin. Each ecological niche presents a …
gastrointestinal, and genitourinary tracts; and the skin. Each ecological niche presents a …
Molecular basis of bacterial resistance to chloramphenicol and florfenicol
S Schwarz, C Kehrenberg, B Doublet… - FEMS microbiology …, 2004 - academic.oup.com
Chloramphenicol (Cm) and its fluorinated derivative florfenicol (Ff) represent highly potent
inhibitors of bacterial protein biosynthesis. As a consequence of the use of Cm in human …
inhibitors of bacterial protein biosynthesis. As a consequence of the use of Cm in human …
Prophage genomics
C Canchaya, C Proux, G Fournous… - Microbiology and …, 2003 - Am Soc Microbiol
The majority of the bacterial genome sequences deposited in the National Center for
Biotechnology Information database contain prophage sequences. Analysis of the …
Biotechnology Information database contain prophage sequences. Analysis of the …
Multilocus sequence ty** system for group B streptococcus
N Jones, JF Bohnsack, S Takahashi… - Journal of clinical …, 2003 - Am Soc Microbiol
ABSTRACT A multilocus sequence ty** (MLST) system was developed for group B
streptococcus (GBS). The system was used to characterize a collection (n= 152) of globally …
streptococcus (GBS). The system was used to characterize a collection (n= 152) of globally …
Group B streptococcal maternal colonization and neonatal disease: molecular mechanisms and preventative approaches
Group B Streptococcus (GBS) colonizes the gastrointestinal and vaginal epithelium of a
significant percentage of healthy women, with potential for ascending intrauterine infection …
significant percentage of healthy women, with potential for ascending intrauterine infection …
The double life of group B Streptococcus: asymptomatic colonizer and potent pathogen
Group B streptococcus (GBS) is a β-hemolytic gram-positive bacterium that colonizes the
lower genital tract of approximately 18% of women globally as an asymptomatic member of …
lower genital tract of approximately 18% of women globally as an asymptomatic member of …
Identification of a Universal Group B Streptococcus Vaccine by Multiple Genome Screen
Group B Streptococcus (GBS) is a multiserotype bacterial pathogen representing a major
cause of life-threatening infections in newborns. To develop a broadly protective vaccine, we …
cause of life-threatening infections in newborns. To develop a broadly protective vaccine, we …