Synthesis and functionalization of porphyrins through organometallic methodologies
This review focuses on the postfunctionalization of porphyrins and related compounds
through catalytic and stoichiometric organometallic methodologies. The employment of …
through catalytic and stoichiometric organometallic methodologies. The employment of …
Ruthenium-catalyzed azide alkyne cycloaddition reaction: scope, mechanism, and applications
JR Johansson, T Beke-Somfai… - Chemical …, 2016 - ACS Publications
The ruthenium-catalyzed azide alkyne cycloaddition (RuAAC) affords 1, 5-disubstituted 1, 2,
3-triazoles in one step and complements the more established copper-catalyzed reaction …
3-triazoles in one step and complements the more established copper-catalyzed reaction …
Glycosylated porphyrins, phthalocyanines, and other porphyrinoids for diagnostics and therapeutics
As deaths from preventable diseases abate, cancer is becoming one of the leading causes
of death in the world. Photodynamic therapy (PDT) is a noninvasive treatment for cancer …
of death in the world. Photodynamic therapy (PDT) is a noninvasive treatment for cancer …
Heteroatom-containing porphyrin analogues
The heteroatom-containing porphyrin analogues or core-modified porphyrins that resulted
from the replacement of one or two pyrrole rings with other five-membered heterocycles …
from the replacement of one or two pyrrole rings with other five-membered heterocycles …
Customizable Porphyrin Platform Enables Folate Receptor PET Imaging Using Copper-64
Folate receptors including folate receptor α (FRα) are overexpressed in up to 90% of ovarian
cancers. Ovarian cancers overexpressing FRα often exhibit high degrees of drug resistance …
cancers. Ovarian cancers overexpressing FRα often exhibit high degrees of drug resistance …
Discovery of a robust and efficient homogeneous silver (I) catalyst for the cycloaddition of azides onto terminal alkynes
J McNulty, K Keskar - European Journal of Organic Chemistry, 2012 - Wiley Online Library
A highly efficient, chemically stable, and well‐defined homogeneous silver (I) catalyst is
reported for the cycloaddition of azides onto terminal alkynes (Ag‐AAC reaction). The Ag …
reported for the cycloaddition of azides onto terminal alkynes (Ag‐AAC reaction). The Ag …
Synthetic approaches to asymmetric phthalocyanines and their analogues
This review summarizes synthetic strategies for the preparation of asymmetric
phthalocyanines and their analogues. Cross-condensation between two phthalonitrile …
phthalocyanines and their analogues. Cross-condensation between two phthalonitrile …
“Click”-reaction: An alternative tool for new architectures of porphyrin based derivatives
The copper catalyzed azide-alkyne cycloaddition (CuAAC), known as “click reaction” is a
well-known method used for the construction of complex molecular architectures. Due to its …
well-known method used for the construction of complex molecular architectures. Due to its …
Synthesis and biological evaluation of a library of glycoporphyrin compounds
A library of glycosylated porphyrins (glycoporphyrins) was prepared and the compounds
were evaluated for their photodynamic therapy (PDT) activity against the oesophageal …
were evaluated for their photodynamic therapy (PDT) activity against the oesophageal …
Site-selective multi-porphyrin attachment enables the formation of a next-generation antibody-based photodynamic therapeutic
Herein we present a significant step towards next-generation antibody-based photodynamic
therapeutics. Site-selective modification of a clinically relevant monoclonal antibody, with a …
therapeutics. Site-selective modification of a clinically relevant monoclonal antibody, with a …