Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

Aptamers are molecular recognition elements made of nucleic acids. Diverse synthetic
aptamers have been discovered in a large number of SELEX experiments since 1990. This …

RNA aptamers and RNA aptamer-based devices can be genetically encoded and
expressed in cells to probe and manipulate cellular function. However, their usefulness in …

DNA and RNA nanotechnology has been used for the development of dynamic molecular
devices. In particular, programmable enzyme-free nucleic acid circuits, such as catalytic …

The chemical composition of cells at the molecular level determines their growth,
differentiation, structure, and function. Probing this composition is powerful because it …

Food safety has always been a hot issue of social concern, and biosensing has been widely
used in the field of food safety detection. Compared with traditional aptamer‐based …

Seeing is not only believing; it also includes understanding. Cellular imaging with GFP in
live cells has been transformative in many research fields. Modulation of cellular regulation …

Fluorescent RNA aptamers are useful as markers for tracking RNA molecules inside cells
and for creating biosensor devices. Förster resonance energy transfer (FRET) based on …

Aptamers are nucleic acid bioreceptors that have been widely utilized for a variety of
biosensing applications, including in vivo detection methods that would not be possible with …

Aptamer-based molecular switches that undergo a binding-induced conformational change
have proven valuable for a wide range of applications, such as imaging metabolites in cells …