Metal ions, metal chelators and metal chelating assay as antioxidant method

İ Gulcin, SH Alwasel - Processes, 2022 - mdpi.com
Heavy metals are essential for a wide range of biological processes, including the growth
and reproduction of cells, synthesis of biomolecules, many enzymatic reactions, and the …

[HTML][HTML] Modulation of intracellular copper levels as the mechanism of action of anticancer copper complexes: Clinical relevance

MV Babak, D Ahn - Biomedicines, 2021 - mdpi.com
Copper (Cu) is a vital element required for cellular growth and development; however, even
slight changes in its homeostasis might lead to severe toxicity and deleterious medical …

[HTML][HTML] Metabolic changes induced by heavy metal copper exposure in human ovarian granulosa cells

J Lin, L Wang, M Huang, G Xu, M Yang - Ecotoxicology and Environmental …, 2024 - Elsevier
Copper (Cu) is a common heavy metal and a hazardous environmental pollutant. Emerging
epidemiological evidence suggests that Cu exposure is associated with female infertility …

Advances in copper complexes as anticancer agents

C Santini, M Pellei, V Gandin, M Porchia… - Chemical …, 2014 - ACS Publications
Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …

Evaluation of metal-based antimicrobial compounds for the treatment of bacterial pathogens

A Evans, KA Kavanagh - Journal of medical microbiology, 2021 - microbiologyresearch.org
Antimicrobial resistance (AMR) is one of the greatest global health challenges of modern
times and its prevalence is rising worldwide. AMR within bacteria reduces the efficacy of …

Chemotherapy-induced peripheral neuropathy: What do we know about mechanisms?

VA Carozzi, A Canta, A Chiorazzi - Neuroscience letters, 2015 - Elsevier
Cisplatin, oxaliplatin, paclitaxel, vincristine and bortezomib are some of the most effective
drugs successfully employed (alone or in combinations) as first-line treatment for common …

Copper (II) and zinc (II) coordination compounds of non-steroidal anti-inflammatory drugs: Structural features and antioxidant activity

G Psomas - Coordination Chemistry Reviews, 2020 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used analgesic, anti-
inflammatory and antipyretic agents with known side-effects. The most important NSAIDs are …

Cellular consequences of copper complexes used to catalyze bioorthogonal click reactions

DC Kennedy, CS McKay, MCB Legault… - Journal of the …, 2011 - ACS Publications
Copper toxicity is a critical issue in the development of copper-based catalysts for copper (I)-
catalyzed azide–alkyne cycloaddition (CuAAC) reactions for applications in living systems …

Biomedical applications of copper ionophores

V Oliveri - Coordination Chemistry Reviews, 2020 - Elsevier
Copper dyshomeostasis is associated with a plethora of diseases, supporting the possibility
of applying copper ionophores to regenerate the metal homeostasis and treat copper …

Trace copper (II) ions detection and removal from water using novel ligand modified composite adsorbent

MR Awual, M Ismael, T Yaita, SA El-Safty… - Chemical Engineering …, 2013 - Elsevier
A highly selective mesoporous composite adsorbent is proposed for simultaneous detection
and removal of Cu (II) ions in natural waters. The adsorbent was developed using the …