Diagnosis and management of autoimmune hepatitis

L Muratori, AW Lohse, M Lenzi - Bmj, 2023 - bmj.com
Autoimmune hepatitis is an inflammatory disease of the liver of unknown cause that may
progress to liver cirrhosis and end stage liver failure if diagnosis is overlooked and treatment …

[HTML][HTML] Nomenclature, diagnosis and management of drug-induced autoimmune-like hepatitis (DI-ALH): An expert opinion meeting report

RJ Andrade, GP Aithal, YS de Boer, R Liberal… - Journal of …, 2023 - Elsevier
Drug-induced liver injury (DILI) can mimic almost all other liver disorders. A phenotype
increasingly ascribed to drugs is autoimmune-like hepatitis (ALH). This article summarises …

Autoimmune hepatitis

BT Beretta-Piccoli, G Mieli-Vergani… - The Rose and Mackay …, 2024 - Elsevier
Autoimmune hepatitis (AIH) is an inflammatory liver disease, affecting mainly females,
characterized by elevated transaminase and immunoglobulin G (IgG) levels, interface …

[HTML][HTML] An open-label randomised-controlled trial of azathioprine vs. mycophenolate mofetil for the induction of remission in treatment-naive autoimmune hepatitis

RJ Snijders, AEC Stoelinga, TJG Gevers, S Pape… - Journal of …, 2024 - Elsevier
Background & Aims Patients with autoimmune hepatitis (AIH) almost invariably require
lifelong immunosuppressive treatment. There is genuine concern about the efficacy and …

Incidence and predictors of hepatocellular carcinoma in patients with autoimmune hepatitis

F Colapietro, P Maisonneuve, E Lytvyak, U Beuers… - Journal of …, 2024 - Elsevier
Background and Aims Autoimmune hepatitis (AIH) is a rare chronic liver disease of unknown
aetiology; the risk of hepatocellular carcinoma (HCC) remains unclear and risk factors are …

Lack of complete biochemical response in autoimmune hepatitis leads to adverse outcome: first report of the IAIHG retrospective registry

CD Slooter, FF Van Den Brand, A Lleo, F Colapietro… - Hepatology, 2024 - journals.lww.com
Methods: This retrospective, observational, multicenter study included all patients with a
clinical diagnosis of AIH from the IAIHG-RR. The quality assessment consisted of external …

Long-term outcomes of patients with type 1 or 2 autoimmune hepatitis presenting in childhood

G Maggiore, O Bernard, A Mosca, E Ballot… - Journal of …, 2023 - Elsevier
Background & Aims In children with autoimmune hepatitis, uncertainties include outcomes
associated with type 2 hepatitis, the possibility of and criteria for attempting withdrawal of …

Rituximab is a safe and effective alternative treatment for patients with autoimmune hepatitis: Results from the ColHai registry

M Riveiro‐Barciela, A Barreira‐Díaz… - Liver …, 2024 - Wiley Online Library
Abstract Background and Aims Small series suggest that rituximab could be effective as
treatment for autoimmune hepatitis (AIH), although data are scarce. We aimed to evaluate …

[HTML][HTML] Autoimmune hepatitis: Current and future therapies

NS Reau, CS Lammert… - Hepatology …, 2024 - journals.lww.com
Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease that can lead to cirrhosis
and liver failure. AIH can present in all ages, races, and ethnicities, but it predominantly …

Therapeutic modulation of the liver immune microenvironment

H Tilg, TE Adolph, F Tacke - Hepatology, 2023 - journals.lww.com
Inflammation is a hallmark of progressive liver diseases such as chronic viral or immune-
mediated hepatitis, alcohol-associated liver disease, and NAFLD. Preclinical and clinical …