Arterial spin labeling perfusion of the brain: emerging clinical applications

S Haller, G Zaharchuk, DL Thomas, KO Lovblad… - Radiology, 2016 - pubs.rsna.org
Arterial spin labeling (ASL) is a magnetic resonance (MR) imaging technique used to assess
cerebral blood flow noninvasively by magnetically labeling inflowing blood. In this article, the …

MRI of healthy brain aging: A review

ME MacDonald, GB Pike - NMR in Biomedicine, 2021 - Wiley Online Library
We present a review of the characterization of healthy brain aging using MRI with an
emphasis on morphology, lesions, and quantitative MR parameters. A scope review found …

Current state and guidance on arterial spin labeling perfusion MRI in clinical neuroimaging

T Lindner, DS Bolar, E Achten, F Barkhof… - Magnetic resonance …, 2023 - Wiley Online Library
This article focuses on clinical applications of arterial spin labeling (ASL) and is part of a
wider effort from the International Society for Magnetic Resonance in Medicine (ISMRM) …

Extending the Human Connectome Project across ages: Imaging protocols for the Lifespan Development and Aging projects

MP Harms, LH Somerville, BM Ances, J Andersson… - Neuroimage, 2018 - Elsevier
Abstract The Human Connectome Projects in Development (HCP-D) and Aging (HCP-A) are
two large-scale brain imaging studies that will extend the recently completed HCP Young …

The Lifespan Human Connectome Project in Development: A large-scale study of brain connectivity development in 5–21 year olds

LH Somerville, SY Bookheimer, RL Buckner… - Neuroimage, 2018 - Elsevier
Recent technological and analytical progress in brain imaging has enabled the examination
of brain organization and connectivity at unprecedented levels of detail. The Human …

A neuroradiologist's guide to arterial spin labeling MRI in clinical practice

M Grade, JA Hernandez Tamames, FB Pizzini… - Neuroradiology, 2015 - Springer
Arterial spin labeling (ASL) is a non-invasive MRI technique to measure cerebral blood flow
(CBF). This review provides a practical guide and overview of the clinical applications of …

The utility of cerebral blood flow as a biomarker of preclinical Alzheimer's disease

CC Hays, ZZ Zlatar, CE Wierenga - Cellular and molecular neurobiology, 2016 - Springer
There is accumulating evidence suggesting that changes in brain perfusion are present long
before the clinical symptoms of Alzheimer's disease (AD), perhaps even before amyloid-β …

Applications of arterial spin labeled MRI in the brain

JA Detre, H Rao, DJJ Wang, YF Chen… - Journal of Magnetic …, 2012 - Wiley Online Library
Perfusion provides oxygen and nutrients to tissues and is closely tied to tissue function while
disorders of perfusion are major sources of medical morbidity and mortality. It has been …

Pediatric sports-related concussion produces cerebral blood flow alterations

TA Maugans, C Farley, M Altaye, J Leach… - Pediatrics, 2012 - publications.aap.org
Objectives: The pathophysiology of sports-related concussion (SRC) is incompletely
understood. Human adult and experimental animal investigations have revealed structural …

[HTML][HTML] Cerebral blood flow measured by arterial spin labeling MRI at resting state in normal aging and Alzheimer's disease

N Zhang, ML Gordon, TE Goldberg - Neuroscience & Biobehavioral …, 2017 - Elsevier
Arterial spin labeling (ASL) magnetic resonance imaging uses arterial blood water as an
endogenous tracer to measure cerebral blood flow (CBF). In this review, based on ASL …