[HTML][HTML] Biomarkers for type 2 diabetes

M Laakso - Molecular Metabolism, 2019 - Elsevier
Background The prevalence and incidence of type 2 diabetes (T2D), representing> 90% of
all cases of diabetes, are increasing rapidly worldwide. Identification of individuals at high …

MicroRNA signatures as future biomarkers for diagnosis of diabetes states

S Vasu, K Kumano, CM Darden, I Rahman… - Cells, 2019 - mdpi.com
Diabetes results from the inability of pancreatic islets to maintain blood glucose
concentrations within a normal physiological range. Clinical features are usually not …

Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis

HJ Taylor, YH Hung, N Narisu… - Proceedings of the …, 2023 - National Acad Sciences
Genetic studies have identified≥ 240 loci associated with the risk of type 2 diabetes (T2D),
yet most of these loci lie in non-coding regions, masking the underlying molecular …

Extracellular vesicle encapsulated microRNAs in patients with type 2 diabetes are affected by metformin treatment

V Ghai, TK Kim, A Etheridge, T Nielsen… - Journal of Clinical …, 2019 - mdpi.com
Recently, microRNAs (miRNAs) in circulating extracellular vesicles (EVs), have emerged as
a source of potential biomarkers for various pathophysiological conditions, including …

Role of autophagy and evaluation the effects of microRNAs 214, 132, 34c and prorenin receptor in a rat model of focal segmental glomerulosclerosis

D Yildirim, O Bender, ZF Karagoz, F Helvacioglu… - Life Sciences, 2021 - Elsevier
Aims Focal segmental glomerulosclerosis (FSGS) is the common cause of chronic renal
disease worldwide. Although there are many etiologic factors which have common theme of …

[HTML][HTML] Hsa_circ_0007478 aggravates NLRP3 inflammasome activation and lipid metabolism imbalance in ox-LDL-stimulated macrophage via miR-765/EFNA3 axis

B Ye, X Liang, Y Zhao, X Cai, Z Wang, S Lin… - Chemico-biological …, 2022 - Elsevier
Coronary heart disease can be effectively prevented by alleviating atherosclerotic plaque
progression. Ox-LDL-induced inflammatory response in macrophages is a critical factor in …

Metformin decreases miR-122, miR-223 and miR-29a in women with polycystic ovary syndrome

PB Udesen, D Glintborg, AE Sørensen… - Endocrine …, 2020 - ec.bioscientifica.com
Metformin is associated with increased insulin sensitivity, whereas oral contraceptive pills
(OCP) could increase the risk for type 2 diabetes (T2D) in women with polycystic ovary …

MicroARN para la detección temprana de diabetes mellitus tipo 2: revisión bibliográfica

JLM Altamirano, ÁR López - Salud, Ciencia y Tecnología, 2023 - dialnet.unirioja.es
Introducción: La Diabetes Mellitus (DM) es una alteración del metabolismo de la glucosa de
múltiple etiología, representa más del 90% de los casos de diabetes alrededor del mundo …

Circulating nucleic acid-based biomarkers of type 2 diabetes

F Padilla-Martinez, G Wojciechowska… - International Journal of …, 2021 - mdpi.com
Type 2 diabetes (T2D) is a deficiency in how the body regulates glucose. Uncontrolled T2D
will result in chronic high blood sugar levels, eventually resulting in T2D complications …

[HTML][HTML] Changes in circulating microRNAs-99/100 and reductions of visceral and ectopic fat depots in response to lifestyle interventions: the CENTRAL trial

Y Heianza, K Krohn, Q Xue, AY Meir, S Ziesche… - The American Journal of …, 2022 - Elsevier
Background MicroRNAs (miRNAs) are short noncoding RNAs and important
posttranscriptional regulators of gene expression. Adipose tissue is a major source of …