Exposure to stress during critical periods in development can have severe long-term
consequences, increasing overall risk on psychopathology. One of the key stress response …

We present a comprehensive overview of the neurobiology of unipolar major depression
and antidepressant drug action, integrating data from affective neuroscience, neuro-and …

This review aims to discuss the evidence supporting the link between chronic stress,
cognitive function and mental health. Over the years, the associations between these …

The brain is the central organ of stress and adaptation to stress because it perceives and
determines what is threatening, as well as the behavioral and physiological responses to the …

During the perinatal period, the brain is particularly sensitive to remodelling by
environmental factors. Adverse early‐life experiences, such as stress exposure or …

Brain cells are continuously exposed to corticosteroid hormones, although the levels vary
(eg, after stress). Corticosteroids alter neural activity via two receptor types …

Because the brain undergoes dramatic changes during fetal development it is vulnerable to
environmental insults. There is evidence that maternal stress and anxiety during pregnancy …

Abstract Background/Aims: Accumulating evidence from a relatively small number of
prospective studies indicates that exposure to prenatal stress profoundly influences the …

Early life stress increases the risk for develo** stress-related pathologies later in life.
Recent studies in rats suggest that mild early life stress, rather than being overall …

Exposure to environmental enrichment can beneficially influence the behavior and enhance
synaptic plasticity. The aim of the present study was to investigate the mediated effects of …