Breast cancer is the most common cancer in women, responsible for over half a million
deaths in 2020. Almost 75% of FDA-approved drugs are mainly nitrogen-and sulfur …

Aroyl‐S, N‐ketene acetals represent a peculiar class of heterocyclic merocyanines,
compounds bearing pronounced and rather short dipoles with great push‐pull …

Coumarin derivatives occur widely in nature and are a part of both traditional and modern
advancements in synthesis and application. To date, thousands of coumarin derivatives …

Ligand-controlled rhodium (I)-catalyzed denitrogenative transformations of a range of 4-vinyl-
1, 2, 3-thiadiazoles possessing electron-donating substituents at the C5-position of the …

This book provides an update on heterocyclic compounds that serve as key components of
anti-cancer agents administered in pre-clinical settings. Many of the compounds highlighted …

In present work, some new 7-hydroxy-4-methyl coumarin derivatives have been synthesized
by environmental benign and mechano-chemical methods and compounds were …

Background: Bimetallic catalysis plays a major role in boosting the catalytic performance of
monometallic counterparts due to the synergetic effect. Materials and Methods: In the …

Isoxazole-5 (4H)-ones are heteropentacycle compounds found in several bioactive
molecules with pharmaceutical and agrochemical properties. A well-known multicomponent …

Phospholipase A2 (PLA2) promotes inflammation via lipid mediators and releases
arachidonic acid (AA), and these enzymes have been found to be elevated in a variety of …

Abstract A novel series of 2, 3-dihydro-1H-pyrazol-4-ylnaphthalene-1, 4-diones is
synthesized via one-pot, multi-component condensation of ethyl acetoacetate, 4 …