Genetics of rheumatic fever and rheumatic heart disease
Rheumatic heart disease (RHD) is a complication of group A streptococcal infection that
results from a complex interaction between the genetic make-up of the host, the infection …
results from a complex interaction between the genetic make-up of the host, the infection …
AraPheno and the AraGWAS Catalog 2020: a major database update including RNA-Seq and knockout mutation data for Arabidopsis thaliana
Genome-wide association studies (GWAS) are integral for studying genotype-phenotype
relationships and gaining a deeper understanding of the genetic architecture underlying trait …
relationships and gaining a deeper understanding of the genetic architecture underlying trait …
Accurate machine learning-based germination detection, prediction and quality assessment of three grain crops
Background Assessment of seed germination is an essential task for seed researchers to
measure the quality and performance of seeds. Usually, seed assessments are done …
measure the quality and performance of seeds. Usually, seed assessments are done …
The benefits of permutation-based genome-wide association studies
Linear mixed models (LMMs) are a commonly used method for genome-wide association
studies (GWAS) that aim to detect associations between genetic markers and phenotypic …
studies (GWAS) that aim to detect associations between genetic markers and phenotypic …
High-dimensional immune profiling identifies a biomarker to monitor dimethyl fumarate response in multiple sclerosis
Dimethyl fumarate (DMF) is an immunomodulatory treatment for multiple sclerosis (MS).
Despite its wide clinical use, the mechanisms underlying clinical response are not …
Despite its wide clinical use, the mechanisms underlying clinical response are not …
Genome-wide study updates in the International Genetics and Translational Research in Transplantation Network (iGeneTRAiN)
The prevalence of end-stage renal disease (ESRD) and the number of kidney transplants
performed continues to rise every year, straining the procurement of deceased and living …
performed continues to rise every year, straining the procurement of deceased and living …
Integrating genetic analysis of germplasm wealth for enhanced selection and improvement in olive (Olea europaea L.): insights from leaves
W Wu, M Shao, J Qi, G **, R Zhang, Y Yao, C Jiang - Plant Cell Reports, 2024 - Springer
Abstract Key Message High-throughput next-generation sequencing of 161 olive germplas.
33 samples were selected as core olive germplasm and Fingerprints were constructed. After …
33 samples were selected as core olive germplasm and Fingerprints were constructed. After …
Neuroimaging PheWAS (phenome-wide association study): a free cloud-computing platform for big-data, brain-wide imaging association studies
Large-scale, case-control genome-wide association studies (GWASs) have revealed genetic
variations associated with diverse neurological and psychiatric disorders. Recent advances …
variations associated with diverse neurological and psychiatric disorders. Recent advances …
Population-aware permutation-based significance thresholds for genome-wide association studies
Motivation Permutation-based significance thresholds have been shown to be a robust
alternative to classical Bonferroni significance thresholds in genome-wide association …
alternative to classical Bonferroni significance thresholds in genome-wide association …
MultiGWAS: An integrative tool for Genome Wide Association Studies in tetraploid organisms
L Garreta, I Cerón‐Souza, MR Palacio… - Ecology and …, 2021 - Wiley Online Library
The genome‐wide association studies (GWASs) are essential to determine the genetic
bases of either ecological or economic phenotypic variation across individuals within …
bases of either ecological or economic phenotypic variation across individuals within …