Two-component signal transduction systems enable bacteria to sense, respond, and adapt
to a wide range of environments, stressors, and growth conditions. In the prototypical two …

The bacterial cell envelope is the first and major line of defence against threats from the
environment. It is an essential and yet vulnerable structure that gives the cell its shape and …

Acinetobacter baumannii forms biofilms on abiotic surfaces, a phenotype that may explain its
ability to survive in nosocomial environments and to cause device-related infections in …

Summary The WalK/WalR (aka YycG/YycF) two‐component system (TCS), originally
identified in Bacillus subtilis, is very highly conserved and specific to low G+ C Gram …

Understanding protein− protein interactions is central to our understanding of almost all
complex biological processes. Computational tools exploiting rapidly growing genomic …

Adaptation of bacteria to the prevailing environmental and nutritional conditions is often
mediated by two‐component signal transduction systems (TCS). The Bacillus subtilis YycFG …

The human pathogen Staphylococcus aureus successfully colonizes its primary reservoir,
the nasal cavity, most likely by regulatory adaptation to the nose environment. Cotton rats …

The glycopeptide antibiotic vancomycin acts by binding to the D-alanyl-D-alanine terminus
of the cell wall precursor lipid II in the cytoplasmic membrane. The purpose of this study was …

Protein phosphorylation on serine, threonine and tyrosine is recognized as a major tool of
signal transduction in bacteria. However, progress in the field has been hampered by the …

BACKGROUND: Protein phosphorylation has emerged as one of the major post
translational modifications in bacteria, involved in regulating a myriad of physiological …