Type III secretion systems (T3SSs) are protein transport nanomachines that are found in
Gram-negative bacterial pathogens and symbionts. Resembling molecular syringes, T3SSs …

Citrobacter rodentium is a mucosal pathogen of mice that shares several pathogenic
mechanisms with enteropathogenic Escherichia coli (EPEC) and enterohaemorrhagic E. coli …

STING is an ER-associated membrane protein that is critical for innate immune sensing of
pathogens. STING-mediated activation of the IFN-I pathway through the TBK1/IRF3 …

Bacteria with two cell membranes (diderms) have evolved complex systems for protein
secretion. These systems were extensively studied in some model bacteria, but the …

Most Escherichia coli strains live harmlessly in the intestines and rarely cause disease in
healthy individuals. Nonetheless, a number of pathogenic strains can cause diarrhea or …

Bacterial flagella and type III secretion system (T3 SS) are evolutionarily related molecular
transport machineries. Flagella mediate bacterial motility; the T3 SS delivers virulence …

Microbial pathogens possess a diversity of weapons that disrupt host homeostasis and
immune defenses, thus resulting in the establishment of infection. The best-characterized …

Edwardsiella piscicida is an Enterobacteriaceae that is abundant in water and causes food
and waterborne infections in fish, animals, and humans. The bacterium causes …

Bacteria-mediated cancer therapy has become a topic of interest under the broad umbrella
of oncotherapy. Among many bacterial species, Salmonella remains at the forefront due to …

Biofilms are complex bacterial assemblages with a defined three‐dimensional architecture,
attached to solid surfaces, and surrounded by a self‐produced matrix generally composed of …