Macrophages are innate immune cells that form a 3D network in all our tissues, where they
phagocytose dying cells and cell debris, immune complexes, bacteria and other waste …

Studies on monocyte and macrophage biology and differentiation have revealed the
pleiotropic activities of these cells. Macrophages are tissue sentinels that maintain tissue …

Monocytes and macrophages have crucial and distinct roles in tissue homeostasis and
immunity, but they also contribute to a broad spectrum of pathologies and are thus attractive …

The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

The paradigm that macrophages that reside in steady-state tissues are derived from
embryonic precursors has never been investigated in the intestine, which contains the …

Macrophages are myeloid immune cells that are strategically positioned throughout the
body tissues, where they ingest and degrade dead cells, debris, and foreign material and …

The molecular and cellular mechanisms that underlie the many roles of macrophages in
health and disease states in vivo remain poorly understood. The purpose of this Review is to …

Microglia constitute a highly specialized network of tissue-resident immune cells that is
important for the control of tissue homeostasis and the resolution of diseases of the CNS …

Self-maintaining resident macrophages populate all mammalian organs. In addition to their
role as immune sentinels, macrophages perform day-to-day functions essential to tissue …

Tissue-resident macrophages have pivotal functions for tissue defense and homeostasis.
Two main discoveries have changed our current understanding of macrophage …