Central regulation of stress-evoked peripheral immune responses

KL Chan, WC Poller, FK Swirski… - Nature Reviews …, 2023 - nature.com
Stress-linked psychiatric disorders, including anxiety and major depressive disorder, are
associated with systemic inflammation. Recent studies have reported stress-induced …

[HTML][HTML] Mitochondrial uncoupling: a key controller of biological processes in physiology and diseases

S Demine, P Renard, T Arnould - Cells, 2019 - mdpi.com
Mitochondrial uncoupling can be defined as a dissociation between mitochondrial
membrane potential generation and its use for mitochondria-dependent ATP synthesis …

Obesity induces PD-1 on macrophages to suppress anti-tumour immunity

JE Bader, MM Wolf, GL Lupica-Tondo, MZ Madden… - Nature, 2024 - nature.com
Obesity is a leading risk factor for progression and metastasis of many cancers,, yet can in
some cases enhance survival,–and responses to immune checkpoint blockade therapies …

Factors associated with hospital admission and critical illness among 5279 people with coronavirus disease 2019 in New York City: prospective cohort study

CM Petrilli, SA Jones, J Yang, H Rajagopalan… - bmj, 2020 - bmj.com
Objective To describe outcomes of people admitted to hospital with coronavirus disease
2019 (covid-19) in the United States, and the clinical and laboratory characteristics …

Factors associated with hospitalization and critical illness among 4,103 patients with COVID-19 disease in New York City

CM Petrilli, SA Jones, J Yang, H Rajagopalan… - MedRxiv, 2020 - medrxiv.org
Background Little is known about factors associated with hospitalization and critical illness
in Covid-19 positive patients. Methods We conducted a cross-sectional analysis of all …

Gut microbiota as a trigger for metabolic inflammation in obesity and type 2 diabetes

TPM Scheithauer, E Rampanelli, M Nieuwdorp… - Frontiers in …, 2020 - frontiersin.org
The gut microbiota has been linked to the development of obesity and type 2 diabetes (T2D).
The underlying mechanisms as to how intestinal microbiota may contribute to T2D are only …

Toll-like receptor signaling rewires macrophage metabolism and promotes histone acetylation via ATP-citrate lyase

MA Lauterbach, JE Hanke, M Serefidou, MSJ Mangan… - Immunity, 2019 - cell.com
Toll-like receptor (TLR) activation induces inflammatory responses in macrophages by
activating temporally defined transcriptional cascades. Whether concurrent changes in the …

Adipogenesis as a potential anti-obesity target: A review of pharmacological treatment and natural products

J Jakab, B Miškić, Š Mikšić, B Juranić… - … syndrome and obesity, 2021 - Taylor & Francis
Obesity is recognized as a severe threat to overall human health and is associated with type
2 diabetes mellitus, dyslipidemia, hypertension, and cardiovascular diseases. Abnormal …

Coronavirus disease 2019 hospitalizations attributable to cardiometabolic conditions in the United States: a comparative risk assessment analysis

M O'Hearn, J Liu, F Cudhea, R Micha… - Journal of the …, 2021 - ahajournals.org
BACKGROUND Risk of coronavirus disease 2019 (COVID‐19) hospitalization is robustly
linked to cardiometabolic health. We estimated the absolute and proportional COVID‐19 …

Protective effects of curcumin in cardiovascular diseases—Impact on oxidative stress and mitochondria

FF Cox, A Misiou, A Vierkant, N Ale-Agha, M Grandoch… - Cells, 2022 - mdpi.com
Cardiovascular diseases (CVDs) contribute to a large part of worldwide mortality. Similarly,
two of the major risk factors for these diseases, aging and obesity, are also global problems …