MicroRNAs (miRNAs) are a group of small non-coding RNAs that post-transcriptionally
control expression of genes by targeting mRNAs. miRNA alterations partake in the …

Alterations in microRNAs (miRNAs) expression are causative in the initiation and
progression of human cancers. The molecular events responsible for the widespread …

Circular RNAs (circRNAs) represent a class of widespread and diverse endogenous RNAs
that may regulate gene expression in eukaryotes. However, the regulation and function of …

Noncoding RNAs plays an important role in hepatocellular carcinoma (HCC). Here, we
show that miR-124 was downregulated in HCC tissues and that the ectopic expression of …

MicroRNA (miRNA; miR) is a functionally small non-coding RNA and can negatively
regulate gene expression by directly binding to the target gene. Some miRNAs are closely …

DNA methylation is the most studied epigenetic mark and CpG methylation is central to
many biological processes and human diseases. Since cancer has highlighted the …

While the eukaryotic genome is the same throughout all somatic cells in an organism, there
are specific structures and functions that discern one type of cell from another. These …

Polycomb Group (PcG) proteins are transcriptional repressors that epigenetically modify
chromatin and participate in the establishment and maintenance of cell fates. These proteins …

Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …

MicroRNAs (miRNAs) comprise species of short noncoding RNA that regulate gene
expression post‐transcriptionally. Recent studies have demonstrated that epigenetic …