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The mammalian blood-testis barrier: its biology and regulation
DD Mruk, CY Cheng - Endocrine reviews, 2015 - academic.oup.com
Spermatogenesis is the cellular process by which spermatogonia develop into mature
spermatids within seminiferous tubules, the functional unit of the mammalian testis, under …
spermatids within seminiferous tubules, the functional unit of the mammalian testis, under …
Natural innate and adaptive immunity to cancer
The immune system can identify and destroy nascent tumor cells in a process termed cancer
immunosurveillance, which functions as an important defense against cancer. Recently …
immunosurveillance, which functions as an important defense against cancer. Recently …
Asymmetric and symmetric stem-cell divisions in development and cancer
SJ Morrison, J Kimble - nature, 2006 - nature.com
Listen to an interview with Sean Morrison on the stem cells podcast Much has been made of
the idea that asymmetric cell division is a defining characteristic of stem cells that enables …
the idea that asymmetric cell division is a defining characteristic of stem cells that enables …
Molecular requirements for epithelial–mesenchymal transition during tumor progression
Epithelial–mesenchymal transitions (EMTs) occur as key steps during embryonic
morphogenesis, and are now implicated in the progression of primary tumors towards …
morphogenesis, and are now implicated in the progression of primary tumors towards …
Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and sha** tumor immunogenicity
Cellular transformation and tumor development result from an accumulation of mutational
and epigenetic changes that alter normal cell growth and survival pathways. For the last 100 …
and epigenetic changes that alter normal cell growth and survival pathways. For the last 100 …
A physical and functional map of the human TNF-α/NF-κB signal transduction pathway
Signal transduction pathways are modular composites of functionally interdependent sets of
proteins that act in a coordinated fashion to transform environmental information into a …
proteins that act in a coordinated fashion to transform environmental information into a …
Modelling glandular epithelial cancers in three-dimensional cultures
Little is known about how the genotypic and molecular abnormalities associated with
epithelial cancers actually contribute to the histological phenotypes observed in tumours in …
epithelial cancers actually contribute to the histological phenotypes observed in tumours in …
The cytoskeleton and cancer
A Hall - Cancer and Metastasis Reviews, 2009 - Springer
Cancer is a disease in which many of the characteristics of normal cell behavior are lost or
perturbed. Uncontrolled cell proliferation and inappropriate cell survival are common …
perturbed. Uncontrolled cell proliferation and inappropriate cell survival are common …
Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse
N Ohnishi, H Yuasa, S Tanaka, H Sawa… - Proceedings of the …, 2008 - pnas.org
Infection with cagA-positive Helicobacter pylori is associated with gastric adenocarcinoma
and gastric mucosa-associated lymphoid tissue (MALT) lymphoma of B cell origin. The cagA …
and gastric mucosa-associated lymphoid tissue (MALT) lymphoma of B cell origin. The cagA …
[HTML][HTML] Polarity complex proteins
The formation of functional epithelial tissues involves the coordinated action of several
protein complexes, which together produce a cell polarity axis and develop cell–cell …
protein complexes, which together produce a cell polarity axis and develop cell–cell …