Associations of social isolation and loneliness with later dementia
Background and Objectives To investigate the independent associations of social isolation
and loneliness with incident dementia and to explore the potential neurobiological …
and loneliness with incident dementia and to explore the potential neurobiological …
The VLPFC-engaged voluntary emotion regulation: Combined TMS-fMRI evidence for the neural circuit of cognitive reappraisal
A clear understanding of the neural circuit underlying emotion regulation (ER) is important
for both basic and translational research. However, a lack of evidence based on combined …
for both basic and translational research. However, a lack of evidence based on combined …
Social Withdrawal, Loneliness, and Health in Schizophrenia: Psychological and Neural Mechanisms
Abstract Background and Hypothesis Some of the most debilitating aspects of schizophrenia
and other serious mental illnesses (SMI) are the impairments in social perception …
and other serious mental illnesses (SMI) are the impairments in social perception …
Plasma proteomic signatures of social isolation and loneliness associated with morbidity and mortality
The biology underlying the connection between social relationships and health is largely
unknown. Here, leveraging data from 42,062 participants across 2,920 plasma proteins in …
unknown. Here, leveraging data from 42,062 participants across 2,920 plasma proteins in …
[HTML][HTML] Hikikomori: A society-bound syndrome of severe social withdrawal
B Dong, D Li, GB Baker - Psychiatry and Clinical …, 2022 - ncbi.nlm.nih.gov
Background: Hikikomori, a severe and often prolonged social withdrawal observed primarily
in young people, was first described in Japan, but cases have now been reported in many …
in young people, was first described in Japan, but cases have now been reported in many …
The impact of hearing loss on cognitive impairment: the mediating role of depressive symptoms and the moderating role of social relationships
Background Given the potentially negative effects of hearing loss on mental health and
cognitive function, it is critical to gain a better understanding of the mechanisms underlying …
cognitive function, it is critical to gain a better understanding of the mechanisms underlying …
Abnormal brain structure is associated with social and communication deficits in children with autism Spectrum disorder: a voxel-based morphometry analysis
MX Xu, XD Ju - Brain Sciences, 2023 - mdpi.com
Structural magnetic resonance imaging (sMRI) studies have shown abnormalities in the
brain structure of ASD patients, but the relationship between structural changes and social …
brain structure of ASD patients, but the relationship between structural changes and social …
Impaired social concept processing in persons with autistic-like traits
Situated models suggest that social concepts are grounded in interpersonal experience.
However, few studies have tested this notion experimentally, and none has targeted …
However, few studies have tested this notion experimentally, and none has targeted …
Hearing loss and subjective well-being among older adults: Mediating effect of social activity and cognitive function
X Cao, B Yang, J Zhou - Clinical Gerontologist, 2023 - Taylor & Francis
Objectives To examine the relationship between hearing loss and subjective well-being
(SWB) and to investigate the mediating roles of social activity and cognitive function in the …
(SWB) and to investigate the mediating roles of social activity and cognitive function in the …
The role of PDE11A4 in social isolation-induced changes in intracellular signaling and neuroinflammation
K Pilarzyk, R Farmer, L Porcher, MP Kelly - Frontiers in Pharmacology, 2021 - frontiersin.org
Phosphodiesterase 11A (PDE11A), an enzyme that degrades cyclic nucleotides (cAMP and
cGMP), is the only PDE whose mRNA expression in brain is restricted to the hippocampal …
cGMP), is the only PDE whose mRNA expression in brain is restricted to the hippocampal …