An overview on neurobiology and therapeutics of attention-deficit/hyperactivity disorder

BS Da Silva, EH Grevet, LCF Silva, JKN Ramos… - Discover Mental …, 2023 - Springer
Abstract Attention-Deficit/Hyperactivity Disorder (ADHD) is a prevalent psychiatric condition
characterized by developmentally inappropriate symptoms of inattention and/or …

Map** and comparing fMRI connectivity networks across species

M Pagani, D Gutierrez‐Barragan… - Communications …, 2023 - nature.com
Technical advances in neuroimaging, notably in fMRI, have allowed distributed patterns of
functional connectivity to be mapped in the human brain with increasing spatiotemporal …

Mendelian randomization analyses reveal causal relationships between brain functional networks and risk of psychiatric disorders

C Mu, X Dang, XJ Luo - Nature human behaviour, 2024 - nature.com
Dysfunction of brain resting-state functional networks has been widely reported in
psychiatric disorders. However, the causal relationships between brain resting-state …

Genetic architecture of the structural connectome

M Wainberg, NJ Forde, S Mansour, I Kerrebijn… - Nature …, 2024 - nature.com
Myelinated axons form long-range connections that enable rapid communication between
distant brain regions, but how genetics governs the strength and organization of these …

Harnessing artificial intelligence in multimodal omics data integration: paving the path for the next frontier in precision medicine

Y Nam, J Kim, SH Jung, J Woerner… - Annual Review of …, 2024 - annualreviews.org
The integration of multiomics data with detailed phenotypic insights from electronic health
records marks a paradigm shift in biomedical research, offering unparalleled holistic views …

Interindividual variation in human cortical cell type abundance and expression

N Johansen, S Somasundaram, KJ Travaglini… - Science, 2023 - science.org
Single-cell transcriptomic studies have identified a conserved set of neocortical cell types
from small postmortem cohorts. We extended these efforts by assessing cell type variation …

The genetic architecture of multimodal human brain age

J Wen, B Zhao, Z Yang, G Erus, I Skampardoni… - Nature …, 2024 - nature.com
The complex biological mechanisms underlying human brain aging remain incompletely
understood. This study investigated the genetic architecture of three brain age gaps (BAG) …

Transcriptomic decoding of regional cortical vulnerability to major depressive disorder

J Zhu, X Chen, B Lu, XY Li, ZH Wang, LP Cao… - Communications …, 2024 - nature.com
Previous studies in small samples have identified inconsistent cortical abnormalities in
major depressive disorder (MDD). Despite genetic influences on MDD and the brain, it is …

Statistical learning methods for neuroimaging data analysis with applications

H Zhu, T Li, B Zhao - Annual review of biomedical data science, 2023 - annualreviews.org
The aim of this review is to provide a comprehensive survey of statistical challenges in
neuroimaging data analysis, from neuroimaging techniques to large-scale neuroimaging …

Heritability of individualized cortical network topography

KM Anderson, T Ge, R Kong, LM Patrick… - Proceedings of the …, 2021 - pnas.org
Human cortex is patterned by a complex and interdigitated web of large-scale functional
networks. Recent methodological breakthroughs reveal variation in the size, shape, and …