Map** and comparing fMRI connectivity networks across species

M Pagani, D Gutierrez‐Barragan… - Communications …, 2023 - nature.com
Technical advances in neuroimaging, notably in fMRI, have allowed distributed patterns of
functional connectivity to be mapped in the human brain with increasing spatiotemporal …

An overview on neurobiology and therapeutics of attention-deficit/hyperactivity disorder

BS Da Silva, EH Grevet, LCF Silva, JKN Ramos… - Discover Mental …, 2023 - Springer
Abstract Attention-Deficit/Hyperactivity Disorder (ADHD) is a prevalent psychiatric condition
characterized by developmentally inappropriate symptoms of inattention and/or …

Transcriptomic decoding of regional cortical vulnerability to major depressive disorder

J Zhu, X Chen, B Lu, XY Li, ZH Wang, LP Cao… - Communications …, 2024 - nature.com
Previous studies in small samples have identified inconsistent cortical abnormalities in
major depressive disorder (MDD). Despite genetic influences on MDD and the brain, it is …

Heritability of individualized cortical network topography

KM Anderson, T Ge, R Kong… - Proceedings of the …, 2021 - National Acad Sciences
Human cortex is patterned by a complex and interdigitated web of large-scale functional
networks. Recent methodological breakthroughs reveal variation in the size, shape, and …

The genetic architecture of biological age in nine human organ systems

J Wen, YE Tian, I Skampardoni, Z Yang, Y Cui… - Nature aging, 2024 - nature.com
Investigating the genetic underpinnings of human aging is essential for unraveling the
etiology of and develo** actionable therapies for chronic diseases. Here, we characterize …

Statistical learning methods for neuroimaging data analysis with applications

H Zhu, T Li, B Zhao - Annual Review of Biomedical Data …, 2023 - annualreviews.org
The aim of this review is to provide a comprehensive survey of statistical challenges in
neuroimaging data analysis, from neuroimaging techniques to large-scale neuroimaging …

Interindividual variation in human cortical cell type abundance and expression

N Johansen, S Somasundaram, KJ Travaglini… - Science, 2023 - science.org
Single-cell transcriptomic studies have identified a conserved set of neocortical cell types
from small postmortem cohorts. We extended these efforts by assessing cell type variation …

Mendelian randomization analyses reveal causal relationships between brain functional networks and risk of psychiatric disorders

C Mu, X Dang, XJ Luo - Nature human behaviour, 2024 - nature.com
Dysfunction of brain resting-state functional networks has been widely reported in
psychiatric disorders. However, the causal relationships between brain resting-state …

Towards interpretable imaging genomics analysis: methodological developments and applications

X Cen, W Dong, W Lv, Y Zhao, F Dubee, AFA Mentis… - Information …, 2024 - Elsevier
Identifying the relationship between imaging features and genetic variation (a term coined
“imaging genomics”) offers valuable insight into the pathogenesis of cancer, as well as …

Harnessing Artificial Intelligence in Multimodal Omics Data Integration: Paving the Path for the Next Frontier in Precision Medicine

Y Nam, J Kim, SH Jung, J Woerner… - Annual Review of …, 2024 - annualreviews.org
The integration of multiomics data with detailed phenotypic insights from electronic health
records marks a paradigm shift in biomedical research, offering unparalleled holistic views …