[HTML][HTML] Synthesis of five-and six-membered cyclic organic peroxides: Key transformations into peroxide ring-retaining products

AO Terent'ev, DA Borisov, VA Vil… - Beilstein Journal of …, 2014 - beilstein-journals.org
The present review describes the current status of synthetic five and six-membered cyclic
peroxides such as 1, 2-dioxolanes, 1, 2, 4-trioxolanes (ozonides), 1, 2-dioxanes, 1, 2 …

Exploration of artemisinin derivatives and synthetic peroxides in antimalarial drug discovery research

OPS Patel, RM Beteck, LJ Legoabe - European journal of medicinal …, 2021 - Elsevier
Malaria is a life-threatening infectious disease caused by protozoal parasites belonging to
the genus Plasmodium. It caused an estimated 405,000 deaths and 228 million malaria …

Synthesis and antioxidant activity of thymol and carvacrol based Schiff bases

D Kumar, DS Rawat - Bioorganic & medicinal chemistry letters, 2013 - Elsevier
Thymol and carvacrol are well known antioxidants found in the extract of the plants of thyme
species. The Schiff bases of 2-iso-propyl-5-methyl-phenol (thymol/1a), 2-tert-butyl-5-methyl …

Novel 4-aminoquinoline-pyrimidine based hybrids with improved in vitro and in vivo antimalarial activity

S Manohar, UC Rajesh, SI Khan… - ACS medicinal …, 2012 - ACS Publications
A class of hybrid molecules consisting of 4-aminoquinoline and pyrimidine were synthesized
and tested for antimalarial activity against both chloroquine (CQ)-sensitive (D6) and …

Synthesis of novel 1, 2, 3-triazole derivatives of isoniazid and their in vitro and in vivo antimycobacterial activity evaluation

D Kumar, G Khare, S Kidwai, AK Tyagi, R Singh… - European journal of …, 2014 - Elsevier
We report herein the synthesis and antimycobacterial activity of 1, 2, 3-triazole derivatives of
isoniazid. Most of the compounds exhibited potent activity against Mycobacterium …

Synthesis of 4‐aminoquinoline‐1, 2, 3‐triazole and 4‐aminoquinoline‐1, 2, 3‐triazole‐1, 3, 5‐triazine Hybrids as Potential Antimalarial Agents

S Manohar, SI Khan, DS Rawat - Chemical Biology & Drug …, 2011 - Wiley Online Library
We report herein synthesis of a series of 4‐aminoquinoline‐1, 2, 3‐triazole and 4‐
aminoquinoline‐1, 2, 3‐triazole‐1, 3, 5‐triazine hybrids and evaluate their antimalarial …

4-Aminoquinoline-pyrimidine hybrids: synthesis, antimalarial activity, heme binding and docking studies

D Kumar, SI Khan, BL Tekwani, P Ponnan… - European Journal of …, 2015 - Elsevier
A series of novel 4-aminoquinoline-pyrimidine hybrids has been synthesized and evaluated
for their antimalarial activity. Several compounds showed promising in vitro antimalarial …

Essential Oils of Five Baccharis Species: Investigations on the Chemical Composition and Biological Activities

JM Budel, M Wang, V Raman, J Zhao, SI Khan… - Molecules, 2018 - mdpi.com
This paper provides a comparative account of the essential oil chemical composition and
biological activities of five Brazilian species of Baccharis (Asteraceae), namely B …

Synthesis, antimalarial activity and cytotoxicity of 4-aminoquinoline–triazine conjugates

S Manohar, SI Khan, DS Rawat - Bioorganic & medicinal chemistry letters, 2010 - Elsevier
A series of 4-aminoquinoline–triazine conjugates with different substitution pattern have
been synthesized and evaluated for their in vitro antimalarial activity against chloroquine …

An overview on the antimalarial activity of 1, 2, 4‐trioxanes, 1, 2, 4‐trioxolanes and 1, 2, 4, 5‐tetraoxanes

M Shukla, K Rathi, M Hassam… - Medicinal Research …, 2024 - Wiley Online Library
The demand for novel, fast‐acting, and effective antimalarial medications is increasing
exponentially. Multidrug resistant forms of malarial parasites, which are rapidly spreading …