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[HTML][HTML] Synthesis of five-and six-membered cyclic organic peroxides: Key transformations into peroxide ring-retaining products
The present review describes the current status of synthetic five and six-membered cyclic
peroxides such as 1, 2-dioxolanes, 1, 2, 4-trioxolanes (ozonides), 1, 2-dioxanes, 1, 2 …
peroxides such as 1, 2-dioxolanes, 1, 2, 4-trioxolanes (ozonides), 1, 2-dioxanes, 1, 2 …
Exploration of artemisinin derivatives and synthetic peroxides in antimalarial drug discovery research
Malaria is a life-threatening infectious disease caused by protozoal parasites belonging to
the genus Plasmodium. It caused an estimated 405,000 deaths and 228 million malaria …
the genus Plasmodium. It caused an estimated 405,000 deaths and 228 million malaria …
Synthesis and antioxidant activity of thymol and carvacrol based Schiff bases
D Kumar, DS Rawat - Bioorganic & medicinal chemistry letters, 2013 - Elsevier
Thymol and carvacrol are well known antioxidants found in the extract of the plants of thyme
species. The Schiff bases of 2-iso-propyl-5-methyl-phenol (thymol/1a), 2-tert-butyl-5-methyl …
species. The Schiff bases of 2-iso-propyl-5-methyl-phenol (thymol/1a), 2-tert-butyl-5-methyl …
Novel 4-aminoquinoline-pyrimidine based hybrids with improved in vitro and in vivo antimalarial activity
A class of hybrid molecules consisting of 4-aminoquinoline and pyrimidine were synthesized
and tested for antimalarial activity against both chloroquine (CQ)-sensitive (D6) and …
and tested for antimalarial activity against both chloroquine (CQ)-sensitive (D6) and …
Synthesis of novel 1, 2, 3-triazole derivatives of isoniazid and their in vitro and in vivo antimycobacterial activity evaluation
We report herein the synthesis and antimycobacterial activity of 1, 2, 3-triazole derivatives of
isoniazid. Most of the compounds exhibited potent activity against Mycobacterium …
isoniazid. Most of the compounds exhibited potent activity against Mycobacterium …
Synthesis of 4‐aminoquinoline‐1, 2, 3‐triazole and 4‐aminoquinoline‐1, 2, 3‐triazole‐1, 3, 5‐triazine Hybrids as Potential Antimalarial Agents
S Manohar, SI Khan, DS Rawat - Chemical Biology & Drug …, 2011 - Wiley Online Library
We report herein synthesis of a series of 4‐aminoquinoline‐1, 2, 3‐triazole and 4‐
aminoquinoline‐1, 2, 3‐triazole‐1, 3, 5‐triazine hybrids and evaluate their antimalarial …
aminoquinoline‐1, 2, 3‐triazole‐1, 3, 5‐triazine hybrids and evaluate their antimalarial …
4-Aminoquinoline-pyrimidine hybrids: synthesis, antimalarial activity, heme binding and docking studies
A series of novel 4-aminoquinoline-pyrimidine hybrids has been synthesized and evaluated
for their antimalarial activity. Several compounds showed promising in vitro antimalarial …
for their antimalarial activity. Several compounds showed promising in vitro antimalarial …
Essential Oils of Five Baccharis Species: Investigations on the Chemical Composition and Biological Activities
This paper provides a comparative account of the essential oil chemical composition and
biological activities of five Brazilian species of Baccharis (Asteraceae), namely B …
biological activities of five Brazilian species of Baccharis (Asteraceae), namely B …
Synthesis, antimalarial activity and cytotoxicity of 4-aminoquinoline–triazine conjugates
S Manohar, SI Khan, DS Rawat - Bioorganic & medicinal chemistry letters, 2010 - Elsevier
A series of 4-aminoquinoline–triazine conjugates with different substitution pattern have
been synthesized and evaluated for their in vitro antimalarial activity against chloroquine …
been synthesized and evaluated for their in vitro antimalarial activity against chloroquine …
An overview on the antimalarial activity of 1, 2, 4‐trioxanes, 1, 2, 4‐trioxolanes and 1, 2, 4, 5‐tetraoxanes
M Shukla, K Rathi, M Hassam… - Medicinal Research …, 2024 - Wiley Online Library
The demand for novel, fast‐acting, and effective antimalarial medications is increasing
exponentially. Multidrug resistant forms of malarial parasites, which are rapidly spreading …
exponentially. Multidrug resistant forms of malarial parasites, which are rapidly spreading …