Hemodynamic forces are fundamental to development. Indeed, much of cardiovascular
morphogenesis reflects a two-way interaction between mechanical forces and the gene …

The heart is the first organ to function in vertebrate embryos. The human heart, for example,
starts beating around the 21st embryonic day. During the initial phase of its pum** action …

This study investigates the physics of the longitudinal stretching-based wave pum**
mechanism, a novel extension of the traditional impedance pump. In its simplest form, an …

Biomechanics affect early cardiac development, from loo** to the development of
chambers and valves. Hemodynamic forces are essential for proper cardiac development …

Asymmetric pum** is a sub-category of valveless pum** in which a flexible tube is
rhythmically compressed in the transverse symmetry plane. Due to the resulting asymmetry …

Asymmetric pum** can be achieved by periodically compressing a flexible tube in its
plane of symmetry using an actuator, as long as the rigid pipes connected to its ends are …

Valveless pum** based on Liebau mechanism entails asymmetrical positioning of the
compression site relative to the attachment sites of the pump's elastic segment to the rest of …

The valveless impedance pump is a simple design that allows the producion or amplification
of a flow without the requirement for valves or impellers. It is based on fluid-filled flexible …

The early embryonic heart is a multi-layered tube consisting of (1) an outer myocardial
tube;(2) an inner endocardial tube; and (3) an extracellular matrix layer interposed between …

Impedance pum** and asymmetric pum** are the main mechanisms of the Liebau
effect, a type of valveless pum**. The primary objective of this study is to enhance the …