The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis
Global tuberculosis incidence has declined marginally over the past decade, and
tuberculosis remains out of control in several parts of the world including Africa and Asia …
tuberculosis remains out of control in several parts of the world including Africa and Asia …
Clinical use of whole genome sequencing for Mycobacterium tuberculosis
Drug-resistant tuberculosis (TB) remains a major challenge to global health and to
healthcare in the UK. In 2014, a total of 6,520 cases of TB were recorded in England, of …
healthcare in the UK. In 2014, a total of 6,520 cases of TB were recorded in England, of …
CARD 2020: antibiotic resistome surveillance with the comprehensive antibiotic resistance database
Abstract The Comprehensive Antibiotic Resistance Database (CARD; https://card. mcmaster.
ca) is a curated resource providing reference DNA and protein sequences, detection models …
ca) is a curated resource providing reference DNA and protein sequences, detection models …
Genome-based prediction of bacterial antibiotic resistance
Clinical microbiology has long relied on growing bacteria in culture to determine
antimicrobial susceptibility profiles, but the use of whole-genome sequencing for antibiotic …
antimicrobial susceptibility profiles, but the use of whole-genome sequencing for antibiotic …
New developments in tuberculosis diagnosis and treatment
CM Gill, L Dolan, LM Piggott, AM McLaughlin - Breathe, 2022 - Eur Respiratory Soc
Tuberculosis (TB) is a major cause of morbidity and mortality worldwide. It is estimated that
25% of the world's population are infected with Mycobacterium tuberculosis, with a 5–10 …
25% of the world's population are infected with Mycobacterium tuberculosis, with a 5–10 …
Advances in diagnosis of Tuberculosis: an update into molecular diagnosis of Mycobacterium tuberculosis
Tuberculosis (TB) is a major cause of deaths by a single infectious agent and has now been
a global public health problem due to increasing numbers of drug-resistant cases. Early and …
a global public health problem due to increasing numbers of drug-resistant cases. Early and …
Evolution of drug resistance in Mycobacterium tuberculosis: a review on the molecular determinants of resistance and implications for personalized care
N Dookie, S Rambaran, N Padayatchi… - Journal of …, 2018 - academic.oup.com
Abstract Drug-resistant TB (DR-TB) remains a significant challenge in TB treatment and
control programmes worldwide. Advances in sequencing technology have significantly …
control programmes worldwide. Advances in sequencing technology have significantly …
Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis
To characterize the genetic determinants of resistance to antituberculosis drugs, we
performed a genome-wide association study (GWAS) of 6,465 Mycobacterium tuberculosis …
performed a genome-wide association study (GWAS) of 6,465 Mycobacterium tuberculosis …
Antimicrobial resistance in rivers: a review of the genes detected and new challenges
P Grenni - Environmental Toxicology and Chemistry, 2022 - Wiley Online Library
River ecosystems are very important parts of the water cycle and an excellent habitat, food,
and drinking water source for many organisms, including humans. Antibiotics are emerging …
and drinking water source for many organisms, including humans. Antibiotics are emerging …
Rapid, comprehensive, and affordable mycobacterial diagnosis with whole-genome sequencing: a prospective study
LJ Pankhurst, C del Ojo Elias, AA Votintseva… - The Lancet …, 2016 - thelancet.com
Background Slow and cumbersome laboratory diagnostics for Mycobacterium tuberculosis
complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome …
complex (MTBC) risk delayed treatment and poor patient outcomes. Whole-genome …