Challenges and opportunities to computationally deconvolve heterogeneous tissue with varying cell sizes using single-cell RNA-sequencing datasets

SK Maden, SH Kwon, LA Huuki-Myers… - Genome biology, 2023 - Springer
Deconvolution of cell mixtures in “bulk” transcriptomic samples from homogenate human
tissue is important for understanding disease pathologies. However, several experimental …

Insights, opportunities and challenges provided by large cell atlases

M Hemberg, F Marini, S Ghazanfar, AA Ajami… - ar** of tissue
architecture and the investigation of gene regulation and cellular crosstalk, which in turn …

Data reuse in agricultural genomics research: challenges and recommendations

A Hafner, V DeLeo, CH Deng, CG Elsik… - …, 2025 - academic.oup.com
The scientific community has long benefited from the opportunities provided by data reuse.
Recognizing the need to identify the challenges and bottlenecks to reuse in the agricultural …