BACKGROUND: The use of bone marrow concentrate (BMC) for treatment of
musculoskeletal disorders has become increasingly popular over the last several years, as …

Pain is the major symptom of osteoarthritis (OA) and is an important factor in strategies to
manage this disease. However, the current standard of care does not provide satisfactory …

Purpose To establish consensus statements on platelet-rich plasma (PRP) for the treatment
of musculoskeletal pathologies. Methods A consensus process on the treatment of PRP …

Bone marrow aspirate concentrate (BMAC) and adipose-derived stromal vascular fraction
(ADSVF) are the most marketed stem cell therapies to treat a variety of conditions in the …

Intervertebral disc (IVD) degeneration is a common cause of low back pain and most spinal
disorders. As IVD degeneration is a major obstacle to the healthy life of so many individuals …

Knee osteoarthritis (KOA) is associated with a high risk of sarcopenia. Both intra-articular
injections (IAIs) and physical therapy (PT) exert benefits in KOA. This network meta-analysis …

Background: The lack of a standardized system for describing cell therapies acts as a barrier
to advancement in clinical and basic research and practice. The aim of this study was to …

Purpose The aim of this study is to evaluate the outcomes of autologous microfragmented
adipose tissue (MFAT) injection in elderly patients with knee osteoarthritis (OA). We …

Background Mesenchymal stem or stromal cells are the most widely used cell therapy to
date. They are heterogeneous, with variations in growth potential, differentiation capacity …

Purpose To provide an updated review of the literature on the use of orthobiologics as a
potential treatment option to alleviate symptoms associated with osteoarthritis (OA), slow the …