While ventricular electromechanics is extensively studied in both physiological and
pathological conditions, four-chamber heart models have only been addressed recently; …

We propose a mathematical and numerical model for the simulation of the heart function that
couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and …

Stroke is a leading cause of death worldwide. With escalating healthcare costs, early non-
invasive stroke risk stratification is vital. The current paradigm of stroke risk assessment and …

This paper provides a review of engineering applications and computational methods used
to analyze the dynamics of heart valve closures in healthy and diseased states …

Atrial fibrillation (AF) alters left atrial (LA) hemodynamics, which can lead to thrombosis in
the left atrial appendage (LAA), systemic embolism and stroke. A personalized risk …

Purpose In this work we performed an imaged-based computational study of the systolic
fluid dynamics in presence of mitral valve regurgitation (MVR). In particular, we compared …

We present a new computational model for the numerical simulation of blood flow in the
human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian …

In this work, we performed a computational image-based study of blood dynamics in the
whole left heart, both in a healthy subject and in a patient with mitral valve regurgitation. We …

Atrial fibrillation (AF) is nowadays the most common human arrhythmia and it is considered
a marker of an increased risk of embolic stroke. It is known that 99% of AF-related thrombi …

Abstract Systolic Anterior Motion (SAM) of the mitral valve–often associated with
Hypertrophic Obstructive Cardiomyopathy (HOCM)–is a cardiac pathology in which a …